..., the pore-forming domain is coloured dark green, linker domain is grey, α-helical shell is yellow, and neuraminidase-like domain is blue. In panels B and C , the Ig-like receptor-binding domains (RBDs) are coloured red, orange, brown and coral for RBD-A, -B, -C and -D, respectively. Note that TcdA4 lacks...

...Elizabeth K.M. Johnstone; Kevin D.G. Pfleger Many receptors are able to undergo heteromerisation, leading to the formation of receptor complexes that may have pharmacological profiles distinct from those of the individual receptors. As a consequence of this, receptor heteromers can be classed...

... is controlled by highly specific receptors to avoid mislocalization and subsequent cellular damage. After binding their soluble cargo in the early stage of the secretory pathway, receptors rely on their own sorting signals to reach their target organelles for ligand delivery, and to recycle back for a new round...