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Keywords: repair
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Biochem Soc Trans (2014) 42 (3): 657–661.
Published: 22 May 2014
... delivered stem cells engraft within lungs, thereby limiting their utility for airway repair. In other organ systems, magnetic targeting has shown promise for improving long-term robust cell engraftment. This technique involves in vitro cell expansion, magnetic actuation and magnetically guided cell...
Biochem Soc Trans (2011) 39 (2): 606–610.
Published: 22 March 2011
... genome recombination Rep repair UvrD Helicases play essential roles in both the actual process of DNA replication and the repair or resuscitation of blocked replication forks. This class of enzymes use the energy derived from hydrolysis of nucleoside triphosphates (usually ATP) to translocate...
Biochem Soc Trans (2009) 37 (1): 74–78.
Published: 20 January 2009
... molecular biology of Hel308, drawing together ideas of how it may contribute to genome stability through the control of recombination, with reference to paradigms developed in bacteria. archaeon Hel308 helicase recombination repair replication Since many stages of replication, repair...
Biochem Soc Trans (2007) 35 (5): 1352–1354.
Published: 25 October 2007
...E. Petermann; T. Helleday DNA lesions resulting from impaired progression of replication forks are implicated in genetic instability and tumorigenesis. Because the cellular response to these lesions poses an important tumorigenesis barrier, the responsible signalling and repair pathways are often...
Biochem Soc Trans (2005) 33 (2): 413–417.
Published: 01 April 2005
...A.D. Metcalfe; M.W.J. Ferguson Biomedical science has made major advances in understanding how cells grow into functioning tissue and the signalling mechanisms used to achieve this are slowly being dissected. Tissue engineering is the application of that knowledge to the building or repairing...
Biochem Soc Trans (2004) 32 (6): 918–919.
Published: 26 October 2004
... of Hmgn1 knockout mice and genetically engineered cell lines that are beginning to reveal the diverse roles that HMGN proteins play in DNA repair and transcription within mammalian cells. 1 email k.west@clinmed.gla.ac.uk 8 7 2004 © 2004 The Biochemical Society 2004 chromatin...
Biochem Soc Trans (2003) 31 (3): 694–698.
Published: 01 June 2003
... pyrimidine dimers (CPDs) and (6–4) photoproducts, can be very efficiently repaired by photoreactivation in this organism. There are two putative photolyase gene homologues in the published genome sequence of Halobacterium sp. NRC-1. We have made a mutant deleted in one of these, phr2 , and confirmed...