...Kotaro Tomuro; Shintaro Iwasaki Ribosome profiling (or Ribo-seq) has emerged as a powerful approach for revealing the regulatory mechanisms of protein synthesis, on the basis of deep sequencing of ribosome footprints. Recent innovations in Ribo-seq technologies have significantly enhanced...

... polysome fractions (Poly-Ribo-Seq) proteome ribosome profiling small open reading frames (smORFs) translation The advent of mass sequencing has provided us with the full sequence of genomes and has given rise to the field of genomics. Initially, gene sequences were identified as containing ORFs...

... and exonic sites bound by splicing regulators in mouse brain tissue. Ribosome profiling has been used to quantify ribosome density on budding yeast mRNAs under different environmental conditions. Post-transcriptional regulation in neurons requires high spatial and temporal precision, as is evident from...