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Keywords: scaffolding domain
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 947–959.
Published: 25 March 2024
... believed by many to be attributable to the highly conserved and versatile scaffolding domain (CSD). However, as the CSD is a hydrophobic domain located by cryoEM to the periphery of the 8S complex, it is predicted to be enmeshed in membrane lipids. This has led some to challenge its ability to interact...