..., scrapie in sheep and CWD (chronic wasting disease) in deer. This review examines the emergence of various TSE strains and their transmission, and discusses disease surveillance and control. 1 To whom correspondence should be addressed (email [email protected] ). 1 8 2006 © 2006...

... disease protein misfolding scrapie CJD, Creutzfeldt-Jakob disease TSE, transmissible spongiform encephalopathy PMCA, protein misfolding cyclic amplification Amyloidogenic Proteins Involved in Neurodegeneration and Therapeutic Implications 32 33 34 35 36 37 38 39 Gabizon, R., Meiner, Z...

... strong evidence to suggest that apart from this difference in resistance a major difference between the isoforms is that the normal prion protein binds copper and has an anti-oxidant function. Brains from Creutzfeldt-Jakob disease patients and brains from mice with experimental mouse scrapie have been...