... Developmental model systems Nuclear organization Sequestration An important question in biology is how cells control which genes are to be turned on and which genes are to be turned off. Deciphering the mechanisms that regulate gene expression could potentially help to treat diseases linked...

... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ATG proteins autophagy degradation lysosomes phagophore sequestration Autophagy is a self-degradative cellular...

... sequestration and down-regulation. Emerging evidence suggests additional functions of endocytosis in mediating GPCR signalling via certain effector pathways, such as mitogen-activated protein kinase modules. The diverse functions of endocytosis raise fundamental questions about the nature of the vesicular...