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Keywords: sialic acid
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Biochem Soc Trans (2022) 50 (2): 935–950.
Published: 06 April 2022
...Kelli A. McCord; Matthew S. Macauley Sialic acid-binding immunoglobulin-like lectins (Siglecs) are important immunomodulatory receptors. Due to differences between human and mouse Siglecs, defining the in vivo roles for human Siglecs (hSiglecs) can be challenging. One solution is the development...
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Biochem Soc Trans (2016) 44 (3): 760–765.
Published: 09 June 2016
...Gavin H. Thomas The sialic acids are a family of 9-carbon sugar acids found predominantly on the cell-surface glycans of humans and other animals within the Deuterostomes and are also used in the biology of a wide range of bacteria that often live in association with these animals. For many...
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Biochem Soc Trans (2016) 44 (1): 166–175.
Published: 09 February 2016
...Nathalie Juge; Louise Tailford; C David Owen Sialidases are a large group of enzymes, the majority of which catalyses the cleavage of terminal sialic acids from complex carbohydrates on glycoproteins or glycolipids. In the gastrointestinal (GI) tract, sialic acid residues are mostly found...
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Biochem Soc Trans (2013) 41 (6): 1475–1481.
Published: 20 November 2013
.... In the present review we focus specifically on the bacterial cell envelope-expressed sialic-acid-containing LOS (lipo-oligosaccharide) structures and Type II CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated) genes that both occur in specific Gram-negative pathogens...
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Biochem Soc Trans (2008) 36 (6): 1467–1471.
Published: 19 November 2008
...Paul R. Crocker; Pierre Redelinghuys Siglecs (sialic acid-binding Ig-like lectins) are mainly expressed in the immune system. Sn (sialoadhesin) (siglec-1), CD22 (siglec-2) and siglec-15 are well conserved, whereas the CD33-related siglecs are undergoing rapid evolution, as reflected in large...
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Biochem Soc Trans (2006) 34 (6): 1024–1027.
Published: 25 October 2006
...T. Avril; H. Attrill; J. Zhang; A. Raper; P.R. Crocker The siglecs (sialic acid-binding Ig-like lectins) are a family of transmembrane receptors expressed in the haemopoietic, immune and nervous systems. The CD33-related siglecs are a distinct subset mostly expressed in the innate immune system...