...Elizabeth C. Townsend; Lindsay R. Kalan For decades research has centered on identifying the ideal balanced skin microbiome that prevents disease and on developing therapeutics to foster this balance. However, this single idealized balance may not exist. The skin microbiome changes across...

...Dana Beiki; Ian M. Eggleston; Charareh Pourzand 5-Aminolevulinic acid-based photodynamic therapy (ALA-PDT) was first implemented over three decades ago and has since been mainly part of clinical practice for the management of pre-cancerous and cancerous skin lesions. Photodynamic therapy relies...

...Lize Delanghe; Irina Spacova; Joke Van Malderen; Eline Oerlemans; Ingmar Claes; Sarah Lebeer The human skin microbiota forms a key barrier against skin pathogens and is important in modulating immune responses. Recent studies identify lactobacilli as endogenous inhabitants of healthy skin, while...

...Magdalena Kiezel-Tsugunova; Alexandra C. Kendall; Anna Nicolaou Human skin has a distinct profile of fatty acids and related bioactive lipid mediators that regulate many aspects of epidermal and dermal homeostasis, including immune and inflammatory reactions. Sebum lipids act as effective...

... the age-related alterations found in different tissue SC populations, highlighting recently identified changes in aged HFSCs (hair-follicle SCs) in the skin. Muscle aging is associated with a loss of muscle mass and strength, and different descriptions of alterations in MuSC number during aging...

... of organs, including skin, the largest organ in the body. Generally, engineered tissue is a combination of living cells and a supporting matrix. Besides serving as burn coverings, engineered skin substitutes can help patients with diabetic foot ulcers. Today, most of these ulcers are treated...