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Keywords: small-molecule inhibitor
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Biochem Soc Trans (2004) 32 (2): 366–377.
Published: 01 April 2004
... various points for therapeutic intervention using either protein-based or small-molecule inhibitors. Unlike other cytokines, chemokines signal via seven-transmembrane GPCRs (G-protein-coupled receptors), which are favoured targets by the pharmaceutical industry, and, as such, they are the first cytokines...
Biochem Soc Trans (2004) 32 (2): 393–396.
Published: 01 April 2004
..., a Biochemical Society Focused Meeting held at Novartis Horsham Research Centre, U.K., 11–12 November 2003 26 January 2004 © 2004 Biochemical Society 2004 cancer isoform-selective inhibitor phosphoinositide 3-kinase (PI 3-kinase) small-molecule inhibitor Abbreviations used...