... (email [email protected] ) . 10 2 2015 © The Authors Journal compilation © 2015 Biochemical Society 2015 endothelium pannexin pharmacology smooth muscle vasculature A key role for purinergic signalling in vascular function has been understood for well-over half...

... calcium microdomain 5′-nucleotidase raft smooth muscle 5′-Nucleotidase is an enzyme that is linked to the outer lipid layer of the plasma membrane via a GPI (glycosylphosphatidylinositol)–lipid anchor and is separated from the intracellular milieu by the inner layer of the lipid bilayer, while...

... systems. In the α-actinin gene, PTB represses the SM (smooth muscle) exon by binding to key sites in the polypyrimidine tract. Repressive binding to these sites is assisted by co-operative binding to additional downstream sites. SM exon splicing can be activated by CELF proteins, which also bind co...