... and METTL14 are important for RGC development in the embryonic brain, where they prevent the expression of late-lineage specific genes that would otherwise push the cell towards premature differentiation and deplete the stem cell pool [ 76 ]. Accordingly, their loss of function in NSCs leads to developmental...

...) 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . epigenetics histones stem cells A fundamental question in developmental biology is how cell...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . planarian regeneration single-cell transcriptomics stem cells Single-cell transcriptomics is a recently developed technology [ 1 ]. However, it has experienced an exponential evolution...

...: Alexander Thompson ( [email protected] ) * Equal contribution by authors. 16 6 2021 21 7 2021 23 7 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 hematopoiesis homeobox genes stem cells...

... regulating stem cells dynamics in homeostasis and regeneration. In this review, we discuss the use of teeth as a model to investigate signaling pathways, providing an overview of the many unique experimental approaches offered by this organ. We discuss how complex networks of signaling pathways modulate...

... on the targeted treatment of OP. Hopefully, our summary will provide a reference to develop some novel strategies for the target therapy of OP. osteoporosis stem cells targeted therapy Correspondence: Shuping Peng ( [email protected] ) or Cijun Shuai ( [email protected] ) * These authors...