...Lin Wang; Chiam Yu Ng; Satyakam Dash; Costas D. Maranas Computational pathway design tools often face the challenges of balancing the stoichiometry of co-metabolites and cofactors, and dealing with reaction rule utilization in a single workflow. To this end, we provide an overview of two...

... 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 asymmetry protein complex protein–protein interactions quaternary structure stoichiometry Many if not most proteins can assemble into complexes in order to carry out their biological...

... at fixed stoichiometry among modular units. ATPase is driven externally. Oxidative phosphorylation and glycogenolysis are the suppliers. We focus on their regulation which involves different controls, but reduces to two principles that enable facile experimental analysis of the supply and demand fluxes...