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Keywords: stress response
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Biochem Soc Trans (2021) BST20201136.
Published: 09 July 2021
... was the discovery of a protein homeostasis mechanism driven by unassembled ribosomal proteins, referred to as the Ribosome Assembly Stress Response (RASTR), that controls RPG transcription through the reversible condensation of Ifh1. Figure 1. Schematic representation of the three categories of...
Biochem Soc Trans (2020) 48 (2): 441–449.
Published: 22 April 2020
... Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . FKBP51 post-translational modification signal transduction stress response The physiological stress response is elicited whenever a change in the...
Biochem Soc Trans (2019) 47 (1): 357–370.
Published: 01 February 2019
... myotube differentiation [ 42 ]. Interestingly, ARTC1—besides its localisation at the plasma membrane—is also present at the endoplasmic reticulum (ER), with its catalytic domain facing the ER lumen; here, ARTC1 can ADP-ribosylate GRP78/Bip, a protein involved in protein folding and ER stress response [ 43...
Biochem Soc Trans (2017) 45 (4): 1007–1014.
Published: 14 July 2017
... ]. Since eIF4E2 is not able to bind to eIF4G1 [ 13 ], it is possible that specific 4G isoforms might also be involved in the stress response. This would not be unprecedented, given that the eIF4G homologue DAP5 has been reported to allow for translation of specific mRNAs following ER stress [ 14...
Biochem Soc Trans (2017) 45 (2): 417–425.
Published: 13 April 2017
... target recognition. Expression of many sRNAs is positively regulated by stress-responsive sigma factors like RpoE and RpoS, and two-component systems like PhoP/Q, Cpx and Rcs. Some of these regulatory RNAs act via a feedback mechanism on their own regulators, which is best reflected by recent discoveries...
Biochem Soc Trans (2016) 44 (2): 541–545.
Published: 11 April 2016
... evolutionarily conserved pathways. * To whom correspondence should be addressed (email ahagai@agri.huji.ac.il ). 25 1 2016 © 2016 Authors; published by Portland Press Limited 2016 autophagy degradation mitochondria stress response Mitochondria perform a variety of essential...
Biochem Soc Trans (2015) 43 (4): 657–662.
Published: 03 August 2015
...; published by Portland Press Limited 2015 antioxidant response element hazard assessment Kelch-like ECH-associated protein 1 (Keap1) nuclear factor erythroid 2-related factor 2 (Nrf2) stress response toxicity The process of evolution has enabled mammalian cells to withstand continuous...
Biochem Soc Trans (2011) 39 (6): 1560–1564.
Published: 21 November 2011
... correspondence should be addressed (email a.bikfalvi@angio.u-bordeaux1.fr ). 12 9 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 angiogenesis chemokine combinatorial therapy resistance to anti-angiogenesis therapy stress response vascular endothelial growth...
Biochem Soc Trans (2010) 38 (4): 928–933.
Published: 26 July 2010
... expression of stress-responsive genes so that the Bacillus can survive the imposition of stress. Hence the stressosome acts as a hub, receiving manifold different stimuli to effect a single outcome. Using single-particle analysis of cryo-electron micrographs, we have been able to reconstruct a series of...
Biochem Soc Trans (2009) 37 (1): 123–126.
Published: 20 January 2009
... are microbial stress-response elements, although it was recently shown that knocking out all known chromosomally located TA loci in Escherichia coli did not have an impact on survival under certain types of stress. The hyperthermophilic crenarchaeon Sulfolobus solfataricus encodes at least 26 vapBC...
Biochem Soc Trans (2006) 34 (1): 7–11.
Published: 20 January 2006
... genes induced by eIF2 phosphorylation are shared between different environmental stresses, eIF2 kinases function in conjunction with other stress-response pathways, such as those regulated by mitogen-activated protein kinases, to elicit gene expression programmes that are tailored for the specific...