... The Authors Journal compilation © 2013 Biochemical Society 2013 alanine scan family A GPCRs family B GPCRs mutagenesis secretin-like GPCR structure–activity relationship CGRP is an abundant 37-amino-acid neuropeptide that is especially found in the sensory nervous system. CGRP is released...

... calcitonin mutagenesis receptor activity-modifying protein secretin-like G-protein-coupled receptor structure–activity relationship GPCRs form a number of families. The best characterized of these are the rhodopsin-like or family A GPCRs. The secretin-like or family B GPCRs form receptors...

... or uptake of the vitamin. Riboswitches offer an attractive target for chemical intervention, and identification of novel ligands would allow a detailed study on structure–activity relationships, as well as potential leads for the development of antimicrobial compounds. To this end, we have developed...