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Keywords: structure–activity relationship
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Biochem Soc Trans (2013) 41 (1): 180–184.
Published: 29 January 2013
... The Authors Journal compilation © 2013 Biochemical Society 2013 alanine scan family A GPCRs family B GPCRs mutagenesis secretin-like GPCR structureactivity relationship Family B GPCRs have a number of conserved proline residues, including a proline towards the middle of TM helix 6...
Biochem Soc Trans (2012) 40 (2): 433–437.
Published: 21 March 2012
... calcitonin mutagenesis receptor activity-modifying protein secretin-like G-protein-coupled receptor structureactivity relationship GPCRs form a number of families. The best characterized of these are the rhodopsin-like or family A GPCRs. The secretin-like or family B GPCRs form receptors...
Biochem Soc Trans (2011) 39 (2): 652–657.
Published: 22 March 2011
... or uptake of the vitamin. Riboswitches offer an attractive target for chemical intervention, and identification of novel ligands would allow a detailed study on structureactivity relationships, as well as potential leads for the development of antimicrobial compounds. To this end, we have developed...