... by the participation of University of Oxford in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC. correlative microscopy cryo-electron tomography cryo-EM in situ subtomogram averaging virus infection...

..., repeating features within the tomogram can be computationally extracted (sub-tomograms), aligned, and averaged, a process known as ‘subtomogram averaging’ (STA), typically improving the resolution to ∼2–3 nm. For exceptionally favourable samples, however, STA is now capable of reaching ∼4 Å resolution...

... has a kinase-ON conformation; and EEEE, which has a kinase-OFF conformation [ 17 ]. Using cryoET and subtomogram averaging (STA), where repeating subvolumes, such as the CSUs within an array, are aligned and averaged, a 3D density map of the TarCF-QEQE CSU was reconstructed at 11.3 Å resolution [ 17...

... The Author(s) 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cryo-electron microscopy cryo-electron tomography subtomogram averaging The electron...