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Keywords: subunit specificity
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Articles

Use of concatamers to study GABA A receptor architecture and function: application to δ-subunit-containing receptors and possible pitfalls

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Erwin Sigel, Kuldeep H. Kaur, Benjamin P. Lüscher, Roland Baur
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (6): 1338–1342.
https://doi.org/10.1042/BST0371338
Published: 19 November 2009
... γ-aminobutyric acid (GABA) γ-aminobutyric acid type A receptor (GABA A receptor) subunit specificity Often, a harmful construct that results in current expression itself, on complementation to a pentamer, results in expression of functional properties that differ substantially from...
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Articles

Impact of subunit positioning on GABA A receptor function

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E. Sigel, R. Baur, N. Boulineau, F. Minier
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 868–871.
https://doi.org/10.1042/BST0340868
Published: 25 October 2006
... of the pentameric ligand-gated ion channel family, including nicotinic acetylcholine receptors, glycine receptors and 5-HT 3 (5-hydroxytryptamine) receptors. benzodiazepine concatenated subunit γ-aminobutyric acid (GABA) γ-aminobutyric acid type A receptor (GABA A receptor) subunit positioning subunit...
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