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Keywords: tau toxicity
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Biochem Soc Trans (2012) 40 (4): 667–671.
Published: 20 July 2012
... decline than NFTs, again suggesting the possibility of a different mechanism for tau toxicity [ 12 ]. If NFTs are not responsible for tau toxicity, what is the toxic species of tau? The existence of pre-fibrillar aggregates of recombinant tau in assembly assays in vitro has been known for some...