...Eric Rubinstein; Clotilde Théry; Pascale Zimmermann Tetraspanins are a family of 33 proteins in mammals believed to play a crucial role in the compartmentalization of various associated proteins within cells and membranes. Recent studies have elucidated the structure of several tetraspanin members...

...: Susana Minguet ( [email protected] ) 29 7 2020 8 10 2020 12 10 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 caveolin flotillins immunopathology lymphocytes tetraspanins Taken together...

...Jonas Franz; Marco Tarantola; Christoph Riethmüller Tetraspanins are ubiquitous membrane proteins that induce local membrane curvature and hence co-ordinate cell-to-cell contacts. This review highlights their role in inflammation, which requires control of the nano-architecture of attachment sites...

...Julien Saint-Pol; Etienne Eschenbrenner; Emmanuel Dornier; Claude Boucheix; Stéphanie Charrin; Eric Rubinstein By interacting directly with partner proteins and with one another, tetraspanins organize a network of interactions referred to as the tetraspanin web. ADAM10 (A Disintegrin...

...Sjoerd J. van Deventer; Vera-Marie E. Dunlock; Annemiek B. van Spriel To facilitate the myriad of different (signaling) processes that take place at the plasma membrane, cells depend on a high degree of membrane protein organization. Important mediators of this organization are tetraspanin proteins...

... biological process, we discovered the role played by tetraspanin-7 (TSPAN7). This member of the tetraspanin family appears to be a positive regulator of actin nucleation and stabilization, through the ARP2/3 complex. By doing so, TSPAN7 limits HIV-1 endocytosis and maintains viral particles on actin-rich...

... to the tendency of CD81 to associate with other tetraspanins and with cell-specific partner proteins, which provide the cells with a signaling platform. CD81 has also been shown to regulate cell migration and invasion, and has therefore been implicated in cancer progression. Indeed, we have recently shown...

...Laura A. Fast; Diana Lieber; Thorsten Lang; Luise Florin Members of the tetraspanin family have been identified as essential cellular membrane proteins in infectious diseases by nearly all types of pathogens. The present review highlights recently published data on the role of tetraspanin CD151...

...Shijing Yue; Kun Zhao; Ulrike Erb; Sanyukta Rana; Margot Zöller Tetraspanins are highly conserved 4-transmembrane proteins which form molecular clusters with a large variety of transmembrane and cytosolic proteins. By these associations tetraspanins are engaged in a multitude of biological...