...Céline Borde; Lisa Bruno; Olivier Espéli Topoisomerases are the main enzymes capable of resolving the topological constraints imposed by DNA transactions such as transcription or replication. All bacteria possess topoisomerases of different types. Although bacteria with circular replicons should...

... interference. Prokaryotic argonautes (pAgos) are much more diverse than eAgos and have been implicated in defense against invading genetic elements. Recently, it was shown that pAgos protect bacterial cells from a topoisomerase poison ciprofloxacin, raising a possibility that they may play a role in DNA...

... of the Biochemical Society 2023 G-quadruplex nucleolin topoisomerases Guanine-rich nucleic acid sequences can fold into non-canonical four-stranded DNA structures referred to as G-quadruplexes or G4 DNAs [ 1 , 2 ]. G4 DNAs consist of G-quartets formed from four guanine molecules interacting via...