... including protein-coding and a variety of non-coding transcription units. Although Pol II can be configured as a durable enzyme capable of transcribing hundreds of kilobases, there is reliable evidence of widespread abortive Pol II transcription termination shortly after initiation, which is often followed...

... in archaea. For none of the homologs of transcription terminators or anti-terminators described in archaea, a function could be assigned convincingly [ 12 ]. But, it is highly likely that protein factors not driving but influencing termination events in maybe unprecedented ways are yet to be described. Many...

... for transcription termination in yeast and mammals [ 25 , 26 ]. After Pol II transcribes a poly(A) signal, the transcript is cleaved by cleavage factors, and the 5′-fragment is polyadenylated. Pol II remains associated with DNA and continues transcription further downstream. XRN2 is thought to degrade the 3...