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Keywords: transcriptional memory
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 821–830.
Published: 25 March 2024
... the parent cell's gene expression pattern, allowing for efficient transcriptional memory after division. Early studies in mammalian cells suggested that transcription factors (TFs) mark genes for swift reactivation, a phenomenon termed ‘mitotic bookmarking’, but conflicting data emerged regarding TF presence...