.... Comparative analysis of proteome and transcriptome variation in mouse PLoS Genet. 2011 7 e1001393 8 Kristensen A.R. Schandorff S. Hoyer-Hansen M. Nielsen M.O. Jaattela M. Dengjel J. Andersen J.S. Ordered organelle degradation during starvation-induced autophagy Mol...

... and mechanisms of action of Tra2β. At a transcriptome-wide level, Tra2β protein binds a matrix of AGAA-rich sequences mapping frequently to exons. Particular tissue-specific alternatively spliced exons contain high concentrations of high scoring Tra2β-binding sites and bind Tra2β strongly in vitro . These top...

... at unprecedented scale and speed. These next-generation technologies make it feasible to sequence not only static genomes, but also entire transcriptomes expressed under different conditions. These and other powerful applications of next-generation sequencing are rapidly revolutionizing the way genomic studies...