...Claire Dunican; Clare Andradi-Brown; Stefan Ebmeier; Athina Georgiadou; Aubrey J. Cunnington The blood transcriptome of malaria patients has been used extensively to elucidate the pathophysiological mechanisms and host immune responses to disease, identify candidate diagnostic and prognostic...

... ]), which has delayed genome sequencing while still allowing transcriptomic approaches. Even in these monocotyledonous species which are taxonomically quite distant from Arabidopsis, it has been possible to use gene sequence knowledge and signalling pathways deciphered in Arabidopsis through omics...

... computational models developmental biology epigenomics eukaryotic gene expression transcriptomics Figure 1. Conceptual framework for cell types and differentiation dynamics. Left: TFs bind to enhancer and promoter regions depending on the chromatin state. All molecules are drawn at a scale of 1:10...

...Emma de Jong; Anthony Bosco The transcriptome represents the entire set of RNA transcripts expressed in a cell, reflecting both the underlying genetic and epigenetic landscape and environmental influences, providing a comprehensive view of functional cellular states at any given time. Recent...

... or determinate, seems to be similar among distantly related species. The availability of a large number of published transcriptomic datasets for plants with different inflorescence architectures, allowed us to identify transcription factor gene families that are differentially expressed in determinate...

... new approaches in advanced microscopy, transcriptomics and metabolomics using zebrafish as a model system have yielded fundamental insights into the mechanistic underpinnings of disease. Correspondence: Andrew G. Cox ( [email protected] ) 25 10 2018 18 12 2018 2 1 2019...

...Amy Switzer; Daniel R. Brown; Sivaramesh Wigneshweraraj Bacterial adaptive responses to biotic and abiotic stresses often involve large-scale reprogramming of the transcriptome. Since nitrogen is an essential component of the bacterial cell, the transcriptional basis of the adaptive response...