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Keywords: tryptophan
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Biochem Soc Trans (2024) 52 (3): 1149–1158.
Published: 30 May 2024
...Keisuke Wakasugi; Takumi Yokosawa The L-tryptophan (Trp) transport system is highly selective for Trp with affinity in the nanomolar range. This transport system is augmented in human interferon (IFN)-γ-treated and indoleamine 2,3-dioxygenase 1 (IDO1)-expressing cells. Up-regulated cellular uptake...
Biochem Soc Trans (2020) 48 (5): 2029–2037.
Published: 11 September 2020
... and complexity of current chemotherapy for antibiotic-resistant disease presents a need for new therapeutic approaches with novel modes of action. M. tuberculosis is an intracellular pathogen that must survive phagocytosis by macrophages, dendritic cells or neutrophils to establish an infection. The tryptophan...
Biochem Soc Trans (2012) 40 (3): 509–514.
Published: 22 May 2012
...James H. Naismith From a protein structural viewpoint, tryptophan is often considered an inert structural amino acid, playing a role as a hydrophobic anchor in membrane proteins or as part of the hydrophobic core of soluble proteins. However, tryptophan is the only polyaromatic amino acid and, from...
Biochem Soc Trans (2008) 36 (6): 1149–1154.
Published: 19 November 2008
... reactive state, presumably an initial ferric-peroxide (compound 0). a.u., arbitrary units. © The Authors Journal compilation © 2008 Biochemical Society 2008 bacterial pathogenesis haem nitric oxide synthase (NOS) radiation resistance tryptophan In mammals, nitric oxide...