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Keywords: tumour microenvironment
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Biochem Soc Trans (2019) 47 (6): 1689–1700.
Published: 05 December 2019
... be misleading or non-predictive for clinical applications. Models mimicking the tumour microenvironment are particularly pivotal for studying tumour pH homeostasis, which is profoundly affected by the diffusion-limited conditions in the tumour. To advance the understanding of the mechanisms and consequences...
Biochem Soc Trans (2012) 40 (6): 1398–1403.
Published: 21 November 2012
... with an inhibitor of Rab function are also discussed. In recent years, the rising importance of stromal cells in the creation of a tumour microenvironment favourable to cancer cell growth and metastasis has emerged. Important actors in this process are CAFs (cancer-associated fibroblasts) [ 43 ], which, among...
Biochem Soc Trans (2011) 39 (5): 1455–1459.
Published: 21 September 2011
..., direct evidence of this has not emerged. In vivo , ps20 stimulated angiogenesis, although expression of WFDC1/ps20 was down-regulated in the reactive stroma tumour microenvironment in prostate cancer. WFDC1 expression is differential in other cancers and inflammatory conditions. Recent studies point...