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Keywords: vanishing white matter (VWM)
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Articles
Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (6): 1298–1310.
Published: 19 November 2009
... eukaryotic initiation factor 2B (eIF2B) protein synthesis vanishing white matter (VWM) As discussed above, the activity of eIF4E is also inhibited by 4E-BPs: these proteins are phosphorylated by mTORC1 [mTOR (mammalian target of rapamycin) complex 1], leading to their release from eIF4E, thereby...
