...-products). Although the impact of AGEs on different forms of vascular diseases has been intensively investigated, the evidence for the involvement of Glo1 and MG is still scarce. Recently, several studies have provided significant evidence for Glo1 having a protective effect on microvascular complications...

... be addressed (email [email protected] ). 19 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 activin receptor-like kinase 1 (ACVRL1) angiogenesis endoglin hereditary haemorrhagic telangiectasia (HHT) transforming growth factor β (TGFβ) vascular disease...

... The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) axon–glial integrity hypoperfusion vascular disease white matter The integrity of the white matter is critical in regulating efficient neuronal communication and maintaining...

... to a fetal gene-expression profile in cardiac myocytes results in cardiac hypertrophy and changes in the expression of many ion channel genes leads to a phenotypic switch from contractile to proliferative smooth muscle cells in vascular diseases such as neointimal hyperplasia and atherosclerosis...

... (sphingosine 1-phosphate) and SPC (sphingosylphosphocholine). Both S1P and SPC can act as vasoconstrictors and may modulate VSMC (vascular smooth muscle cell) phenotype, as observed during the pathogenesis of vascular disease. Recent research has suggested that SPC may act as a pro-inflammatory mediator...

...R.M. Ogborne; S.A. Rushworth; C.A. Charalambos; M.A. O'Connell HO-1 (haem oxygenase-1) is a stress-response enzyme involved in the catabolism of haem. In animal models, it plays a key protective role in vascular disease. HO-1 has anti-inflammatory effects in macrophages and is induced by a range...

... Society 2003 glycoxidation lipoxidation nephropathy pyridoxamine vascular disease Abbreviations used: AGE, advanced glycation end-product; ALE, advanced lipoxidation end-product; CML, N ∊ -(carboxymethyl)lysine; CEL, N ∊ -(carboxyethyl)lysine; MDA, malondialdehyde; PM...