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Keywords: vascular endothelial growth factor receptor 2 (VEGFR-2)
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Biochem Soc Trans (2009) 37 (6): 1189–1192.
Published: 19 November 2009
.... Upon activation by VEGFR-2, c-Cbl, with the help of ubiquitin-conjugating enzymes E1 and E2, acts as an ubiquitin E3 ligase and ubiquitinates PLCγ1. Ub, ubiquitin. angiogenesis endothelial cell phospholipase Cγ1 (PLCγ1) ubiquitination vascular endothelial growth factor receptor 2 (VEGFR-2...