...); published by Portland Press Limited on behalf of the Biochemical Society 2016 cytoskeleton tumor cell adhesion vesicle trafficking Metastasis is the leading cause of death in cancer patients [ 1 , 2 ]. The first step of metastasis is considered to be the epithelial-to-mesenchymal transition...

... the cytoskeleton dynamics with vesicle trafficking during cytokinesis are poorly understood. The highly conserved Golgi phosphoprotein 3 (GOLPH3), functions as a phosphatidylinositol 4-phosphate (PI4P) effector at the Golgi. Recent studies have suggested that GOLPH3 is up-regulated in several cancers...

... adhesion. Loss of TJs has been linked to the pathogenesis of many diseases. The present review focuses on the role of vesicle trafficking in regulation of TJs, in particular trafficking of the TJ protein occludin. We examine how endocytosis and endosomal recycling modulate occludin localization under...

... trafficking. Although the machineries of vesicle trafficking and cell polarity in plants have been individually well addressed, how ROPs co-ordinate those processes is still largely unclear. Recent progress has been made towards an understanding of the co-ordination of ROP signalling and trafficking of PIN...

... ). 29 5 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 cell migration cell motility endocytosis endosomal recycling epithelial cell vesicle trafficking The process of migration involves both generation of a motile phenotype and its continuance...

...Humberto Fernandes; Edward Franklin; Rosario Recacha; Anne Houdusse; Bruno Goud; Amir R. Khan The small GTPase Rab6 regulates vesicle trafficking at the level of Golgi. Recently, the crystal structures of Rab6 in complexes with two unrelated effectors have been determined. The structure of Rab6a...

... metazoan SNARE multicellularity vesicle trafficking The eukaryotic cell encompasses a large system of intracellular membrane-delimited compartments. It is widely assumed that this extensive endomembrane system evolved as a result of a phagotrophic lifestyle by invagination of the plasma membrane...

...S. Wang; S.C. Hsu Exocytosis is a highly ordered vesicle trafficking pathway that targets proteins to the plasma membrane for membrane addition or secretion. Research over the years has discovered many proteins that participate at various stages in the mammalian exocytotic pathway. At the early...

... include enzymes of biosynthetic metabolism, vesicle trafficking, cell signalling and chromatin function. These findings indicate central regulatory roles for 14-3-3s in partitioning carbon among the pathways of sugar, amino acid, nucleotide and protein biosynthesis in plants. Our results also suggest...