...J. Jasper Deuring; Maikel P. Peppelenbosch; Ernst J. Kuipers; C. Janneke van der Woude; Colin de Haar The intestinal tract is covered by a total of 300 square metres of IECs (intestinal epithelial cells) that covers the entire intestinal mucosa. For protection against luminal xenobiotics, pathogens...

... b 5 cytochrome P450 Escherichia coli haemoprotein xenobiotic Figure 1 Targeting of engineered cytochrome b 5 isoforms to E. coli compartments ( A ) Topogenesis of engineered cytochrome b 5 isoforms to various E. coli compartments. ( B ) Non-recombinant ( i ) or recombinant...

... and phenotypic analyses of organisms (both mice and prokaryotes) following genetic modifications of the nat genes are leading to an understanding of the potentially diverse roles of NAT in endogenous and xenobiotic metabolism. These studies have indicated that NAT, particularly in Mycobacteria, has the potential...

... 2001 © 2001 Biochemical Society 2001 apoptosis toxicity xenobiotic genetic disease signal transduction SPT, serine palmitoyltransferase Enzymes that Regulate Lipid Metabolism in Cell Signalling Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its...