... affected. Deciphering how the ENS forms from its progenitor cells, enteric neural crest cells, is an active area of research across various animal models. The vertebrate animal model, zebrafish, has been increasingly leveraged to understand early ENS formation, and over the past 20 years has contributed...

... stressors remain under investigation. In this review, we highlight the zebrafish, Danio rerio , as a potent model of intestinal epithelial development and function. We describe epithelial composition and key regulators of epithelial renewal to promote the zebrafish as an investigative tool to study...

... in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC. BMP endothelial to haematopoietic transition haemogenic endothelium mouse models TGFβ zebrafish TGFβ is a well-known regulator of adult...

... of developmental genes. Zebrafish, perhaps better known for their strength as a model of embryology and organogenesis during development, are coming to the fore as a powerful model for interpreting the role played by chromatin in gene expression. Several recent advances have shown that zebrafish exhibit both...

... 104 13632 13637 10.1073/pnas.0706290104 17698806 42 Gut P. Verdin E. Rejuvenating SIRT1 activators Cell Metab. 2013 17 635 637 10.1016/j.cmet.2013.04.016 23663735 diabetes mellitus metabolic disease mitochondria mitochondrial drugs PK 11195 zebrafish...

... is seeking an understanding of the biochemical basis of inflammation resolution, using the zebrafish model system. Zebrafish larvae are transparent, allowing visualization of GFP (green fluorescent protein)-labelled leucocytes during inflammation in vivo , and they can be readily manipulated by a range...

... with its tyrosine kinase receptors. A number of HS structural features that mediate the specific binding of VEGF 165 , including sulphation requirements, have been determined. In parallel, zebrafish embryos were used as a vertebrate model system to study the role in vascular development of the biosynthetic...

... in zebrafish, mammalian cell lines and, more recently, mammalian tissues, this view has changed to one where clock organization is now seen as being highly decentralized. It is clear that clocks exist in the peripheral tissues of animals as diverse as Drosophila , zebrafish and mammals. In the case...

.... Plakoglobin expression and localization were examined at the protein level during zebrafish embryonic development by Western blotting and confocal microscopy. Plakoglobin was expressed throughout embryo development at the protein level. Western blotting revealed that embryonic plakoglobin protein content...