The pattern of L-alanine uptake in isolated cells of interscapular brown adipose tissue has been determined. The uptake can be divided into the diffusion component (Kd=0.55 min−1) and a saturable Na+-dependent transport (KM=0.87 mM and Vmax=155 nmol/min/106 cells). The saturable component can be subdivided into MeAIB-sensitive (KM=1.63 mM and Vmax=162 nmol/min/106 cells) and MeAIB-insensitive (KM=3.2 mM and Vmax=39.5 nmol/min/106 cells). This kinetic pattern could indicate the presence of transport system (s) that resemble the commonly described transport systems for alanine uptake in several tissues.
Rapid Communication| April 01 1991
L-alanine transport in isolated cells of interscapular brown adipose tissue in rat
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A. Rodríguez-Martín, X. Remesar; L-alanine transport in isolated cells of interscapular brown adipose tissue in rat. Biosci Rep 1 April 1991; 11 (2): 65–71. doi: https://doi.org/10.1007/BF01119193
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