The significant genome compaction in mycoplasmas was made possible by adoption of a parasitic lifestyle. During their evolution and adaptation to a parasitic mode of life the mycoplasmas have developed various genetic systems enabling their attachment to host tissues as well as a highly plastic set of variable surface proteins. The generation of a versatile surface coat through high-frequency phase and size variation provides the organism with a useful tool for immune system avoidance, allowing the mycoplasmas to escape antibody attack, explaining why these minute organisms are such successful parasites.
Research Article| October 01 1999
Adherence of Pathogenic Mycoplasmas to Host Cells
Biosci Rep (1999) 19 (5): 367–372.
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Shmuel Razin; Adherence of Pathogenic Mycoplasmas to Host Cells. Biosci Rep 1 October 1999; 19 (5): 367–372. doi: https://doi.org/10.1023/A:1020204020545
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