The presence of a sodium-stimulated, saturable uptake process for L-cystine is described in brushborder membrane vesicles isolated from rat jejunal mucosa. Concentration-dependence studies indicate the presence of a single transport system for cystine with Km = 0.053 mM and Vmax = 0.633 nmol/mg/15 s. Lysine completely inhibits the uptake of cystine.

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