31P nuclear magnetic resonance (NMR) spectra were obtained from the forearm muscles of 5 subjects before and after performing a muscle stretching (eccentric) exercise routine. Spectra collected before and immediately after exercise showed normal resting phosphorylated metabolite levels and unchanged intracellular pH (pHi). Measurements made on the day following exercise, when muscular pain was apparent, revealed an elevated inorganic phosphate level. No significant changes in other metabolites or pHi were detected. This study gives the first indication of biochemical change following a form of exercise that is associated with considerable muscle pain and damage. The findings may help in understanding pathological processes resulting in pain and damage in muscle.
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July 01 1986
Muscle pain after exercise is linked with an inorganic phosphate increase as shown by31P NMR
R. Aldridge;
R. Aldridge
1Departments of Paediatrics, Medical Physics and Medicine, University College London School of Medicine, University Street, London WC1E 6JJ, UK
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E. B. Cady;
E. B. Cady
1Departments of Paediatrics, Medical Physics and Medicine, University College London School of Medicine, University Street, London WC1E 6JJ, UK
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D. A. Jones;
D. A. Jones
1Departments of Paediatrics, Medical Physics and Medicine, University College London School of Medicine, University Street, London WC1E 6JJ, UK
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G. Obletter
G. Obletter
1Departments of Paediatrics, Medical Physics and Medicine, University College London School of Medicine, University Street, London WC1E 6JJ, UK
*Department Semiotica Medica, University of Chiete, Chiete, Italy
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Publisher: Portland Press Ltd
Received:
July 17 1986
Online ISSN: 1573-4935
Print ISSN: 0144-8463
© 1986 Plenum Publishing Corporation
1986
Biosci Rep (1986) 6 (7): 663–667.
Article history
Received:
July 17 1986
Citation
R. Aldridge, E. B. Cady, D. A. Jones, G. Obletter; Muscle pain after exercise is linked with an inorganic phosphate increase as shown by31P NMR. Biosci Rep 1 July 1986; 6 (7): 663–667. doi: https://doi.org/10.1007/BF01114761
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