Chemical synthesis of different S-forms of dolichyl-P was performed in order to investigate the use of these polyprenes in mannosyl, glucosyl and glucosaminyl transferase reactions. Determination of the Vmax values for a series of dolichyl-P demonstrated that the velocities of transferase reactions with all those dolichyl-P derivatives present in animal tissues are largely the same. The apparent Km values for the various dolichyl-P in the transferase system studied differed, but this property does not appear to have physiological importance.
Effectivity of dolichyl phosphates with different chain lengths as acceptors of nucleotide activated sugars
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P. Löw, E. Peterson, M. Mizuno, T. Takigawa, T. Chojnacki, G. Dallner; Effectivity of dolichyl phosphates with different chain lengths as acceptors of nucleotide activated sugars. Biosci Rep 1 July 1986; 6 (7): 677–683. doi: https://doi.org/10.1007/BF01114763
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