Lactate uptake by liver is markedly increased in late-pregnant and mid-lactating rats without concomitant changes in its availability. Glycerol contribution to the liver 3-C unit uptake is only significant at term gestation (50% of lactate uptake) but almost negligible at mid-lactation (10% of lactate uptake). Pyruvate is only taken up by the liver of 15-day lactating rats. As a general trend, the livers of either pregnant or lactating rats are provided with an enhanced capacity to take up gluconeogenic substrates.
Rapid Communication| July 01 1987
Hepatic uptake of gluconeogenic substrates in late-pregnant and mid-lactating rats
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Javier Casado, Xavier Remesar, Marçal Pastor-Anglada; Hepatic uptake of gluconeogenic substrates in late-pregnant and mid-lactating rats. Biosci Rep 1 July 1987; 7 (7): 587–592. doi: https://doi.org/10.1007/BF01119776
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