A genomic clone for the rat liver gap junction protein (connexin-32) was isolated and characterized by restriction enzyme mapping and sequence analysis. While the complete coding sequence is contained within one uninterrupted block, the 5′-untranslated region of the transcript contains a 6.1 kb intron. Both S1 nuclease protection and primer extension assays indicate multiple transcription start sites. Sequences homologous to cAMP response elements are found near the transcription start sites and within the 3′-end of the intron.
Rapid Communication| October 01 1988
Structure of a gap junction gene: Rat connexin-32
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Todd Miller, Gerhard Dahl, Rudolf Werner; Structure of a gap junction gene: Rat connexin-32. Biosci Rep 1 October 1988; 8 (5): 455–464. doi: https://doi.org/10.1007/BF01121644
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