A theoretical concept is proposed, in order to explain some enigmatic aspects of cellular and molecular biology of eukaryotic organisms. Among these are the C-value paradox of DNA redundancy, the correlation of DNA content and cell size, the disruption of genes at DNA level, the “Chromosome field” data of Lima de Faria (Hereditas93:1, 1980), the “quantal mitosis proposition” of Holtzer et al. (Curr. Top. Dev. Biol.7:229, 1972), the inheritance of morphological patterns, the relations of DNA and chromosome organisation to cellular structure and function, the molecular basis of speciation, etc. The basic proposition of the “Unified Matrix Hypothesis” is that the nuclear DNA has a direct morphogenic function, in addition to its coding function in protein synthesis. This additional genetic information is thought to be largely contained in the non-protein coding transcribed DNA, and in the untranscribed part of the genome.
Review Article| December 01 1988
A Unified Matrix Hypothesis of DNA-directed morphogenesis, protodynamism and growth control
Biosci Rep (1988) 8 (6): 669.
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Klaus Scherrer; A Unified Matrix Hypothesis of DNA-directed morphogenesis, protodynamism and growth control. Biosci Rep 1 December 1988; 8 (6): 669. doi: https://doi.org/10.1007/BF01117345
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