A theoretical concept is proposed, in order to explain some enigmatic aspects of cellular and molecular biology of eukaryotic organisms. Among these are the C-value paradox of DNA redundancy, the correlation of DNA content and cell size, the disruption of genes at DNA level, the “Chromosome field” data of Lima de Faria (Hereditas93:1, 1980), the “quantal mitosis” proposition of Holtzer et al. (Curr. Top. Dev. Biol.7:229 1972), the inheritance of morphological patterns, the relations of DNA and chromosome organisation to cellular structure and function, the molecular basis of speciation, etc. The basic proposition of the “Unified Matrix Hypothesis” is that the nuclear DNA has a direct morphogenic function, in addition to its coding function in protein synthesis. This additional genetic information is thought to be largely contained in the non-protein coding transcribed DNA, and in the untranscribed part of the genome.
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April 01 1989
A unified matrix hypothesis of DNA-directed morphogenesis, protodynamism and growth control1
Klaus Scherrer
Klaus Scherrer
1Institut Jacques Monod, Université PARIS VII, 2 Place Jussieu, F 75251 Paris Cedex 05, France
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Publisher: Portland Press Ltd
Received:
October 15 1988
Online ISSN: 1573-4935
Print ISSN: 0144-8463
© 1989 Plenum Publishing Corporation
1989
Biosci Rep (1989) 9 (2): 157–188.
Article history
Received:
October 15 1988
Citation
Klaus Scherrer; A unified matrix hypothesis of DNA-directed morphogenesis, protodynamism and growth control. Biosci Rep 1 April 1989; 9 (2): 157–188. doi: https://doi.org/10.1007/BF01115994
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