In intact pigeon erythrocytes, adenosine is a potent inhibitor of Na,K-dependent adenosine triphosphatase. In purified cell-membrane preparations, adenosine is only a weak competitive inhibitor of Na,K-ATPase, with respect to ATP. This indicates that adenosine must not be a direct inhibitor of the sodium pump in intact red cells per se; instead, adenosine exerts its inhibitory effect via endogenous cell factors.
Research Article| June 01 1983
Inhibition of Na,K-dependent adenosine triphosphatase by adenosine in intact pigeon erythrocytes
- Views Icon Views
- PDF LinkPDF
- Share Icon Share
Vladimir Leskovac; Inhibition of Na,K-dependent adenosine triphosphatase by adenosine in intact pigeon erythrocytes. Biosci Rep 1 June 1983; 3 (6): 551–555. doi: https://doi.org/10.1007/BF01120699
Download citation file: