Failure of actinomycin D to block the activation of Dol-P-Man synthase in isoproterenol-treated capillary endothelial cells, supported that isoproterenol effect was not mediated by active transcription of the Dol-P-Man synthase gene during a short-term β-adrenoreceptor stimulation. Instead, it was a net effect of protein phosphorylation by cAMP-dependent protein kinase. Using antibody as a probe we have now demonstrated that Dol-P-Man synthase activity is associated with a 32 kDa ER phosphoprotein.
Research Article|June 01 1999
Mannosylphosphodolichol Synthase Activity is Associated with a 32 kDa Phosphoprotein
Dipak K. Banerjee;
Jaime J. Dasilva;
Biosci Rep (1999) 19 (3): 169-177.
- Views Icon Views
- PDF LinkPDF
- Share Icon Share
- Cite Icon Cite
Dipak K. Banerjee, Jaime J. Dasilva, Betzaida Bigio; Mannosylphosphodolichol Synthase Activity is Associated with a 32 kDa Phosphoprotein. Biosci Rep 1 June 1999; 19 (3): 169–177. doi: https://doi.org/10.1023/A:1020221602373
Download citation file: