All methods used to analyze amino acid composition of different enzymes agree well with each other.
They lead to a relationship between amino acid composition and function of proteins.
Cytochrome oxidase is in a class by itself; copper-containing oxidases are closely related as expected.
Research Article| March 01 1983
An analysis of amino acid composition of a few oxidoreductases by different methods
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Ali Naqui, Jean-Claude Vincent; An analysis of amino acid composition of a few oxidoreductases by different methods. Biosci Rep 1 March 1983; 3 (3): 269–273. doi: https://doi.org/10.1007/BF01122459
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