This article is being retracted from Bioscience Reports at the request of the authors following receipt of a notification from a reader, alerting the Editorial Office to multiple similarities between the images within this paper and with those in papers of unrelated authors. Similarities noted between images are described below:

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    Figure 1A Transwell IL6/C918 panel and the Figure 1D Fra2 T98G panel from Luo et al. 2018 (doi: 10.1016/j.prp.2018.09.017)

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    Figure 5C EV siSTAT3 panel and the Figure 4B U251 miR-124-3pmimics/EV panel from Luo et al. 2018 (doi: 10.1016/j.prp.2018.09.017)

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    Figure 5C EV siSTAT3 panel and the Figure 3F bottom +/+ Transwell U251 cells panel from Zhang et al. 2017 (doi: 10.1042/BSR20160643)

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    Figure 5C EV siSTAT3 panel and the Figure 2A +-+ U87MG panel from Su et al. 2019 (doi: 10.1186/s11658-019-0149-x)

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    Figure 5C JunB siSTAT3 panel and the Figure 2B ++- A172 panel from Su et al. 2019 (doi: 10.1186/s11658-019-0149-x)

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    Figure 1B Transwell IL6/OCM1A panel and the Figure 2C Hypoxia - panel from Fei et al. 2018 (doi: 10.1186/s11658-018-0100-6)

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    Figure 6F MMP14 western blot bands and the Figure 3E p-STAT3 bands from Liang et al. 2020 (doi: 10.1042/BSR20193572)

The Editorial Office also identified various duplications within the paper:

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    Between the Figure 2G TJP2 western blots (after being horizontally flipped) and the Figure 4A p-STAT3 C(18 and IL6/C918 bands

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    Between the Figure 2G TJP2 western blots (after being horizontally flipped) and the Figure 5A TJP1 EV bands

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    Between the Figure 3F TJP1 siCtrl bands and the first three Figure F5 STAT3 bands (after a 180-degree rotation)

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    Between the Figure 4A p-STAT3 bands and the first three Figure 5 TJP1 bands

The authors are unable to correct the article and wish to retract the article. The Editor-in-Chief and Editorial Board agree with the retraction.

This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).