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October 2016
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Cover Image
Cover Image
Conserved domains within the NAD+-dependent DNA ligases from bacteria. Image shows the high-resolution structure of E. coli LigA in complex with nicked adenylated DNA from PDB 2OWO, visualized by UCSF Chimera. The various sub-domains of the enzyme are indicated by different colours in the image; the adenylated-DNA molecule is shown in grey. For further information see article e00391. Image kindly provided by Richard Bowater.
ISSN 0144-8463
EISSN 1573-4935
In this Issue
Review Articles
APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway
Biosci Rep (2016) 36 (5): e00377.
Biochemical and structural characterization of DNA ligases from bacteria and archaea
Biosci Rep (2016) 36 (5): e00391.
Original Papers
Epigenetics changes caused by the fusion of human embryonic stem cell and ovarian cancer cells
Biosci Rep (2016) 36 (5): e00378.
IL-1β/HMGB1 signalling promotes the inflammatory cytokines release via TLR signalling in human intervertebral disc cells
Biosci Rep (2016) 36 (5): e00379.
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone
Tadashi Konoshita; Saori Kaeriyama; Machi Urabe; Takahiro Nakaya; Mika Yamada; Mai Ichikawa; Katsushi Yamamoto; Satsuki Sato; Michiko Imagawa; Miki Fujii; Yasukazu Makino; Yasuo Zenimaru; Shigeyuki Wakahara; Jinya Suzuki; Tamotsu Ishizuka; Hiroyuki Nakamura; for the Genomic Disease Outcome Consortium (G-DOC) Study Investigators
Biosci Rep (2016) 36 (5): e00381.
Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells
Biosci Rep (2016) 36 (5): e00382.
Role of the prostaglandin E2 receptor agonists in TGF-β1-induced mesangial cell damage
Biosci Rep (2016) 36 (5): e00383.
Numerical investigation of the haemodynamics in the human fetal umbilical vein/ductus venosus based on the experimental data
Biosci Rep (2016) 36 (5): e00384.
Mechanisms for the inhibition of amyloid aggregation by small ligands
Matteo Ramazzotti; Fabrizio Melani; Laura Marchi; Nadia Mulinacci; Stefano Gestri; Bruno Tiribilli; Donatella Degl'Innocenti
Biosci Rep (2016) 36 (5): e00385.
TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis
Biosci Rep (2016) 36 (5): e00386.
ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells
Ali H. El-Bahrawy; Abdelmetalab Tarhuni; Hogyoung Kim; Venkat Subramaniam; Ilyes Benslimane; Zakaria Y. Abd Elmajeed; Samuel C. Okpechi; Mohamed A. Ghonim; Ramadan A.M. Hemeida; Amira M. Abo-yousef; Gamal A. El-Sherbiny; Ihab T. Abdel-Raheem; Jong Kim; Amarjit S. Naura; A. Hamid Boulares
Biosci Rep (2016) 36 (5): e00388.
Silencing of SOX12 by shRNA suppresses migration, invasion and proliferation of breast cancer cells
Biosci Rep (2016) 36 (5): e00389.
Effects of N-glycosylation of the human cation channel TRPA1 on agonist-sensitivity
Biosci Rep (2016) 36 (5): e00390.
The influence of glycation on a high pressure denaturation of ubiquitin
Monika Kijewska; Karolina Radziszewska; Marta Cal; Mateusz Waliczek; Piotr Stefanowicz; Zbigniew Szewczuk
Biosci Rep (2016) 36 (5): e00393.
Bacillus thuringiensis Cyt2Aa2 toxin disrupts cell membranes by forming large protein aggregates
Biosci Rep (2016) 36 (5): e00394.
Association between selenium intake and the risk of pancreatic cancer: a meta-analysis of observational studies
Biosci Rep (2016) 36 (5): e00395.
MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1
Biosci Rep (2016) 36 (5): e00396.
Wild-type p53 binds to MYC promoter G-quadruplex
Marek Petr; Robert Helma; Alena Polášková; Aneta Krejčí; Zuzana Dvořáková; Iva Kejnovská; Lucie Navrátilová; Matej Adámik; Michaela Vorlíčková; Marie Brázdová
Biosci Rep (2016) 36 (5): e00397.
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice–potential role of the ACE2/AT2R/Mas axis
Glaucia E. Callera; Tayze T. Antunes; Jose W. Correa; Danielle Moorman; Alexey Gutsol; Ying He; Aurelie Nguyen Dinh Cat; Ana M. Briones; Augusto C. Montezano; Kevin D. Burns; Rhian M. Touyz
Biosci Rep (2016) 36 (5): e00398.
Blockade of NF-κB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation in vitro and in vivo
Biosci Rep (2016) 36 (5): e00399.