Volume 41 Issue 6 | Bioscience Reports

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Volume 41, Issue 6

May 2021

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In this issue of Bioscience Reports (volume 41, issue 6), Xu et al. assess how the active compound erianin may affect cell cycle and apoptosis in triple-negative breast cancer cells, and the mechanism by which this occurs.

ISSN 0144-8463

EISSN 1573-4935

Review Articles

Histone deacetylase 10, a potential epigenetic target for therapy

Fajuan Cheng; Bin Zheng; Jianwei Wang; Guiting Zhao; Zhongshun Yao; Zhihong Niu; Wei He

Biosci Rep (2021) 41 (6): BSR20210462.

Abstract

View Articletitled, Histone deacetylase 10, a potential epigenetic target for therapy

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The role of the microbiome in gastrointestinal inflammation

David J. Sanders; Saskia Inniss; Gregory Sebepos-Rogers; Farooq Z. Rahman; Andrew M. Smith

Biosci Rep (2021) 41 (6): BSR20203850.

Abstract

View Articletitled, The role of the microbiome in gastrointestinal inflammation

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Responses and coping methods of different testicular cell types to heat stress: overview and perspectives

Hui Cai; Dezhe Qin; Sha Peng

Biosci Rep (2021) 41 (6): BSR20210443.

Abstract

View Articletitled, Responses and coping methods of different testicular cell types to heat stress: overview and perspectives

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Maturation strategies and limitations of induced pluripotent stem cell-derived cardiomyocytes

Peng Wu; Gang Deng; Xiyalatu Sai; Huiming Guo; Huanlei Huang; Ping Zhu

Biosci Rep (2021) 41 (6): BSR20200833.

Abstract

View Articletitled, Maturation strategies and limitations of induced pluripotent stem cell-derived cardiomyocytes

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Research Articles

Reduction of TMAO level enhances the stability of carotid atherosclerotic plaque through promoting macrophage M2 polarization and efferocytosis

Weihao Shi; Yijun Huang; Zhou Yang; Liang Zhu; Bo Yu

Biosci Rep (2021) 41 (6): BSR20204250.

Abstract

View Articletitled, Reduction of TMAO level enhances the stability of carotid atherosclerotic plaque through promoting macrophage M2 polarization and efferocytosis

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Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia

Michal K. Handzlik; David J. Tooth; Dumitru Constantin-Teodosiu; Paul L. Greenhaff; Mark A. Cole

Biosci Rep (2021) 41 (6): BSR20203170.

Abstract

View Articletitled, Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia

Supplementary data

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Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver–α-cell axis

Qiaofeng Liu; Guangyao Lin; Yan Chen; Wenbo Feng; Yingna Xu; Jianjun Lyu; Dehua Yang; Ming-Wei Wang

Biosci Rep (2021) 41 (6): BSR20210758.

Abstract

View Articletitled, Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver–α-cell axis

Supplementary data

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Targeted next-generation sequencing identifies ABCA4 mutations in Chinese families with childhood-onset and adult-onset Stargardt disease

Ling-hui Qu; Xin Jin; Chao Zeng; Nian-gou Zhou; Yan-hong Liu; Ye Lin

Biosci Rep (2021) 41 (6): BSR20203497.

Abstract

View Articletitled, Targeted next-generation sequencing identifies ABCA4 mutations in Chinese families with childhood-onset and adult-onset Stargardt disease

Supplementary data

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Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases

Qiangqiang Zheng; Shihui Min; Qinghua Zhou

Biosci Rep (2021) 41 (6): BSR20204370.

Abstract

View Articletitled, Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases

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MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells

Yan-yan Zhang; Gao-yun Xiong; Xiao-xing Xie

Biosci Rep (2021) 41 (6): BSR20201397.

Abstract

View Articletitled, MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells

Supplementary data

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Serum biomarker discovery related to pathogenesis in acute coronary syndrome by proteomic approach

Miji Shin; Sora Mun; Sang Hyun Park; Jiyeong Lee; Hee-Gyoo Kang

Biosci Rep (2021) 41 (6): BSR20210344.

Abstract

View Articletitled, Serum biomarker discovery related to pathogenesis in acute coronary syndrome by proteomic approach

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Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma

Lili Li; Rongrong Xie; Guangrong Lu

Biosci Rep (2021) 41 (6): BSR20210760.

Abstract

View Articletitled, Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma

Supplementary data

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LncRNA AWPPH as a prognostic predictor in human cancers in Chinese population: evidence from meta-analysis

Yongfeng Li; Xinmiao Rui; Daobao Chen; Haojun Xuan; Hongjian Yang; Xuli Meng

Biosci Rep (2021) 41 (6): BSR20210012.

Abstract

View Articletitled, LncRNA AWPPH as a prognostic predictor in human cancers in Chinese population: evidence from meta-analysis

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Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing

Yi Jiang; Lihua Wu; Shasha Huang; Pidong Li; Bo Gao; Yongyi Yuan; Siwen Zhang; Guoliang Yu; Yong Gao; Hao Wu; Pu Dai

Biosci Rep (2021) 41 (6): BSR20203740.

Abstract

View Articletitled, Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing

Supplementary data

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Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway

Yonggang Xu; Rong Fang; Jie Shao; Zihao Cai

Biosci Rep (2021) 41 (6): BSR20210093.

Abstract

View Articletitled, Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway

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The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis

Liuting Zeng; Ganpeng Yu; Wensa Hao; Kailin Yang; Hua Chen

Biosci Rep (2021) 41 (6): BSR20210817.

Abstract

View Articletitled, The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis

Supplementary data

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Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology

Jinzhou Zheng; Wenhao Xu; Wangrui Liu; Haijia Tang; Jingen Lu; Kui Yu; Xiaoyun Song; Feng Li; Yu Wang; Rui Wang; Lili Chen; Hailiang Zhang; Yunhua Qiu; Gaomeng Wei; Xiqiu Zhou; Jianfeng Yang

Biosci Rep (2021) 41 (6): BSR20204421.

Abstract

View Articletitled, Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology

Supplementary data

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LncRNA UCA1 elevates the resistance of human leukemia cells to daunorubicin by the PI3K/AKT pathway via sponging miR-613

Qiying Yao; Li Zhang; Yuchuan Wang; Junli Liu; Liu Yang; Yingjie Wang

Biosci Rep (2021) 41 (6): BSR20201389.

Abstract

View Articletitled, LncRNA UCA1 elevates the resistance of human leukemia cells to daunorubicin by the PI3K/AKT pathway via sponging miR-613

Supplementary data

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TagSNP approach for HLA risk allele genotyping of Saudi celiac disease patients: effectiveness and pitfalls

Reham H. Baaqeel; Babajan Banaganapalli; Hadiah Bassam Al Mahdi; Mohammed A. Salama; Bakr H. Alhussaini; Meshari A. Alaifan; Yagoub Bin-Taleb; Noor Ahmad Shaik; Jumana Yousuf Al-Aama; Ramu Elango; Omar I. Saadah

Biosci Rep (2021) 41 (6): BSR20210509.

Abstract

View Articletitled, TagSNP approach for HLA risk allele genotyping of Saudi celiac disease patients: effectiveness and pitfalls

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Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes

Jiaying Lou; Jialin Dong; Ruijun Xu; Hui Zeng; Lijuan Fang; Yi Wu; Yang Liu; Shibing Wang

Biosci Rep (2021) 41 (6): BSR20204186.

Abstract

View Articletitled, Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes

Supplementary data

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The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice

Maria E. Hammarlund; Vladimer Darsalia; Filip Mjörnstedt; Bagmi Pattanaik; Carina Mallard; Eridan Rocha-Ferreira; Cesare Patrone; Maria E. Johansson

Biosci Rep (2021) 41 (6): BSR20210736.

Abstract

View Articletitled, The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice

Supplementary data

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Sublethal hyperthermia enhances anticancer activity of doxorubicin in chronically hypoxic HepG2 cells through ROS-dependent mechanism

Qi Wang; Hui Zhang; Qian-qian Ren; Tian-he Ye; Yi-ming Liu; Chuan-sheng Zheng; Guo-feng Zhou; Xiang-wen Xia

Biosci Rep (2021) 41 (6): BSR20210442.

Abstract

View Articletitled, Sublethal hyperthermia enhances anticancer activity of doxorubicin in chronically hypoxic HepG2 cells through ROS-dependent mechanism

Supplementary data

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Exploring the biosynthetic pathway of lignin in Acorus tatarinowii Schott using de novo leaf and rhizome transcriptome analysis

Shengxiang Zhang; Liqiang Zhao; Chunmiao Shan; Yuanyuan Shi; Kelong Ma; Jiawen Wu

Biosci Rep (2021) 41 (6): BSR20210006.

Abstract

View Articletitled, Exploring the biosynthetic pathway of lignin in Acorus tatarinowii Schott using de novo leaf and rhizome transcriptome analysis

Supplementary data

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Gualou Xiebai Banxia decoction ameliorates Poloxamer 407-induced hyperlipidemia

Mingzhu Luo; Rong Fan; Xiaoming Wang; Junyu Lu; Ping Li; Wenbin Chu; Yonghe Hu; Xuewei Chen

Biosci Rep (2021) 41 (6): BSR20204216.

Abstract

View Articletitled, Gualou Xiebai Banxia decoction ameliorates Poloxamer 407-induced hyperlipidemia

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Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza in diabetic nephropathy using network pharmacology and molecular docking

Lili Zhang; Lin Han; Xinmiao Wang; Yu Wei; Jinghui Zheng; Linhua Zhao; Xiaolin Tong

Biosci Rep (2021) 41 (6): BSR20203520.

Abstract

View Articletitled, Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza in diabetic nephropathy using network pharmacology and molecular docking

Supplementary data

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MicroRNA expression profile in serum reveals novel diagnostic biomarkers for endometrial cancer

Xingchen Fan; Xuan Zou; Cheng Liu; Wenfang Cheng; Shiyu Zhang; Xiangnan Geng; Wei Zhu

Biosci Rep (2021) 41 (6): BSR20210111.

Abstract

View Articletitled, MicroRNA expression profile in serum reveals novel diagnostic biomarkers for endometrial cancer

Supplementary data

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Waardenburg syndrome type II in a Chinese pedigree caused by frameshift mutation in the SOX10 gene

Li Li; Jing Ma; Xiao-li He; Yuan-tao Zhou; Yu Zhang; Quan-dong Chen; Lin Zhang; Biao Ruan; Tie-Song Zhang

Biosci Rep (2021) 41 (6): BSR20193375.

Abstract

View Articletitled, Waardenburg syndrome type II in a Chinese pedigree caused by frameshift mutation in the SOX10 gene

Supplementary data

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Serum CYR61 as a potential biomarker for the diagnosis of esophagogastric junction tumor

Ling-Yu Chu; Jian-Yuan Zhou; Yi-Xuan Zhao; Yan-Ting Ou; Tian Yang; Yu-Hui Peng; Wang-Kai Fang; Yi-Wei Xu; Jian-Jun Xie

Biosci Rep (2021) 41 (6): BSR20204117.

Abstract

View Articletitled, Serum CYR61 as a potential biomarker for the diagnosis of esophagogastric junction tumor

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CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma

Tong Lin; E Zhang; Pei-pei Mai; Ying-zhao Zhang; Xiang Chen; Li-sheng Peng

Biosci Rep (2021) 41 (6): BSR20204312.

Abstract

View Articletitled, CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma

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High glucose–induced Smad3 linker phosphorylation and CCN2 expression are inhibited by dapagliflozin in a diabetic tubule epithelial cell model

Xinlu Pan; Mysore K. Phanish; Deborah L. Baines; Mark E.C. Dockrell

Biosci Rep (2021) 41 (6): BSR20203947.

Abstract

View Articletitled, High glucose–induced Smad3 linker phosphorylation and CCN2 expression are inhibited by dapagliflozin in a diabetic tubule epithelial cell model

Supplementary data

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Elucidation of rutin’s role in inducing caspase-dependent apoptosis via HPV-E6 and E7 down-regulation in cervical cancer HeLa cells

Pratibha Pandey; Fahad Khan; Mohd Farhan; Asif Jafri

Biosci Rep (2021) 41 (6): BSR20210670.

Abstract

View Articletitled, Elucidation of rutin’s role in inducing caspase-dependent apoptosis via HPV-E6 and E7 down-regulation in cervical cancer HeLa cells

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Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways

MiaoShang Su; Yifan He; Sichen Xue; Jueke Yu; Xikai Ren; Nan Huang; Rukkaiya Abdullahi; Manhuan Xu

Biosci Rep (2021) 41 (6): BSR20203639.

Abstract

View Articletitled, Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways

Supplementary data

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Incaspitolide A extracted from Carpesium cernuum induces apoptosis in vitro via the PI3K/AKT pathway in benign prostatic hyperplasia

Xiaoyue Chen; Jingrui Song; Dongbo Yuan; Qing Rao; Kehua Jiang; Shuhui Feng; Guohua Zhu; Chen Yan; Yanmei Li; Jianguo Zhu

Biosci Rep (2021) 41 (6): BSR20210477.

Abstract

View Articletitled, Incaspitolide A extracted from Carpesium cernuum induces apoptosis in vitro via the PI3K/AKT pathway in benign prostatic hyperplasia

Supplementary data

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Corrections

Correction: Preventive role of probiotic bacteria against gastrointestinal diseases in mice caused by Giardia lamblia

Biosci Rep (2021) 41 (6): BSR-2020-4114_COR.

Extract

View Articletitled, Correction: Preventive role of probiotic bacteria against gastrointestinal diseases in mice caused by Giardia lamblia

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Correction: Dexmedetomidine attenuates lipopolysaccharide-induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway

Biosci Rep (2021) 41 (6): BSR-2020-4279_COR.

Extract

View Articletitled, Correction: Dexmedetomidine attenuates lipopolysaccharide-induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway

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Retractions

Retraction: Effects of microRNA-146a on the proliferation and apoptosis of human osteoarthritis chondrocytes by targeting TRAF6 through the NF-κB signaling pathway

Biosci Rep (2021) 41 (6): BSR-2016-0578_RET.

Extract

View Articletitled, Retraction: Effects of microRNA-146a on the proliferation and apoptosis of human osteoarthritis chondrocytes by targeting TRAF6 through the NF-κB signaling pathway

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Retraction: microRNA-98 inhibits the proliferation, invasion, migration and promotes apoptosis of breast cancer cells by binding to HMGA2

Biosci Rep (2021) 41 (6): BSR-2018-0571_RET.

Extract

View Articletitled, Retraction: microRNA-98 inhibits the proliferation, invasion, migration and promotes apoptosis of breast cancer cells by binding to HMGA2

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Retraction: MicroRNA-140-5p suppresses retinoblastoma cell growth via inhibiting c-Met/AKT/mTOR pathway

Biosci Rep (2021) 41 (6): BSR-2018-0776_RET.

Extract

View Articletitled, Retraction: MicroRNA-140-5p suppresses retinoblastoma cell growth via inhibiting c-Met/AKT/mTOR pathway

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Retraction: HOTAIR contributes to cell proliferation and metastasis of cervical cancer via targeting miR-23b/MAPK1 axis

Biosci Rep (2021) 41 (6): BSR-2017-1563_RET.

Extract

View Articletitled, Retraction: HOTAIR contributes to cell proliferation and metastasis of cervical cancer via targeting miR-23b/MAPK1 axis

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Retraction: Suppression of microRNA-135b-5p protects against myocardial ischemia/reperfusion injury by activating JAK2/STAT3 signaling pathway in mice during sevoflurane anesthesia

Biosci Rep (2021) 41 (6): BSR-2017-0186_RET.

Extract

View Articletitled, Retraction: Suppression of microRNA-135b-5p protects against myocardial ischemia/reperfusion injury by activating JAK2/STAT3 signaling pathway in mice during sevoflurane anesthesia

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Retraction: Overexpression of long intergenic noncoding RNA LINC00312 inhibits the invasion and migration of thyroid cancer cells by down-regulating microRNA-197-3p

Biosci Rep (2021) 41 (6): BSR-2017-0109_RET.

Extract

View Articletitled, Retraction: Overexpression of long intergenic noncoding RNA LINC00312 inhibits the invasion and migration of thyroid cancer cells by down-regulating microRNA-197-3p

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Retraction: Study of the biological function of LncRNA LUCAT1 on cervical cancer cells by targeting miR-199b-5p

Biosci Rep (2021) 41 (6): BSR-2020-0422_RET.

Extract

View Articletitled, Retraction: Study of the biological function of LncRNA LUCAT1 on cervical cancer cells by targeting miR-199b-5p

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Retraction: Down-regulation of XIAP enhances the radiosensitivity of esophageal cancer cells in vivo and in vitro

Biosci Rep (2021) 41 (6): BSR-2017-0711_RET.

Extract

View Articletitled, Retraction: Down-regulation of XIAP enhances the radiosensitivity of esophageal cancer cells in vivo and in vitro

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Retraction: Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD

Biosci Rep (2021) 41 (6): BSR-2017-0803_RET.

Extract

View Articletitled, Retraction: Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD

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Retraction: Long noncoding RNA TUG1 promotes proliferation and inhibits apoptosis in multiple myeloma by inhibiting miR-29b-3p

Biosci Rep (2021) 41 (6): BSR-2018-2489_RET.

Extract

View Articletitled, Retraction: Long noncoding RNA TUG1 promotes proliferation and inhibits apoptosis in multiple myeloma by inhibiting miR-29b-3p

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