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Evolving DNA repair synthetic lethality target in cancers

Sanat Kulkarni, Juliette Brownlie, Jennie N Jeyapalan, Nigel P Mongan, Emad A Rakha, Srinivasan Madhusudan

Biosci Rep (2022) BSR20221713.

DOI: https://doi.org/10.1042/BSR20221713

Published: 24 November 2022

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FAD-deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation

Sudipta Panja, David Siegel, Simonetta Camandola, Rafael de Cabo, David Ross, Krishna M.G. Mallela

Biosci Rep (2022) 42 (11): BSR20220643.

DOI: https://doi.org/10.1042/BSR20220643

Published: 14 November 2022

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Tryptophan metabolism and disposition in cancer biology and immunotherapy

Abdulla A.-B. Badawy

Biosci Rep (2022) 42 (11): BSR20221682.

DOI: https://doi.org/10.1042/BSR20221682

Published: 11 November 2022

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Olanzapine add-on treatment promotes neuronal differentiation of neural stem cells compared with fluoxetine alone

Jiantong Sun, Danlian Wu, Guangjuan Xu, Fang Chen, Xinyuan Ding, Linjun Xie, Zhangfeng Yu, Xing Jin

Biosci Rep (2022) 42 (10): BSR20220804.

DOI: https://doi.org/10.1042/BSR20220804

Published: 18 October 2022

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Pharmacokinetic profile of sarcin and thionin from Aspergillus giganteus and in vitro validation against human fungal pathogen

Ramya Ravindhiran, Ramya Krishnamurthy, Karthiga Sivarajan, Jothi Nayaki Sekar, Kumarappan Chidambaram, Ali M Alqahtani, Kavitha Dhandapani

Biosci Rep (2022) 42 (9): BSR20220229.

DOI: https://doi.org/10.1042/BSR20220229

Published: 07 September 2022

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The role of nitric oxide in sepsis-associated kidney injury

Filipe Rodolfo Moreira Borges Oliveira, Jamil Assreuy, Regina Sordi

Biosci Rep (2022) 42 (7): BSR20220093.

DOI: https://doi.org/10.1042/BSR20220093

Published: 11 July 2022

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Andrographolide in atherosclerosis: integrating network pharmacology and in vitro pharmacological evaluation

Shuai Shi, Xinyu Ji, Jingjing Shi, Shuqing Shi, Fei She, Qiuyan Zhang, Yu Dong, Hanming Cui, Yuanhui Hu

Biosci Rep (2022) 42 (7): BSR20212812.

DOI: https://doi.org/10.1042/BSR20212812

Published: 01 July 2022

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Inflammation and serotonin deficiency in major depressive disorder: molecular docking of antidepressant and anti-inflammatory drugs to tryptophan and indoleamine 2,3-dioxygenases

Shazia Dawood, Samina Bano, Abdulla A.-B. Badawy

Biosci Rep (2022) 42 (5): BSR20220426.

DOI: https://doi.org/10.1042/BSR20220426

Published: 27 May 2022

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Prescription drugs and mitochondrial metabolism

Cameron A. Schmidt

Biosci Rep (2022) 42 (4): BSR20211813.

DOI: https://doi.org/10.1042/BSR20211813

Published: 12 April 2022

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Role of ACSL4 in the chemical-induced cell death in human proximal tubule epithelial HK-2 cells

Hiroshi Kuwata, Yuki Tomitsuka, Emiko Yoda, Shuntaro Hara

Biosci Rep (2022) 42 (2): BSR20212433.

DOI: https://doi.org/10.1042/BSR20212433

Published: 09 February 2022

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Acanthopanax senticosus total flavonoids alleviate lipopolysaccharide-induced intestinal inflammation and modulate the gut microbiota in mice

Xiaoya Wang, Xinyu Zhang, Jianqing Su, Xiuling Chu

Biosci Rep (2022) 42 (2): BSR20212670.

DOI: https://doi.org/10.1042/BSR20212670

Published: 07 February 2022

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Lung-protective effect of Punicalagin on LPS-induced acute lung injury in mice

Yibin Zeng, Hongying Zhao, Tong Zhang, Chao Zhang, Yanni He, Lingbo Du, Fuguo Zuo, Wuqing Wang

Biosci Rep (2022) 42 (1): BSR20212196.

DOI: https://doi.org/10.1042/BSR20212196

Published: 24 January 2022

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A commentary on the paper: ‘Evaluation of spice and herb as phytoderived selective modulators of human retinaldehyde dehydrogenases using a simple in vitro method’

Anna Bilska-Wilkosz

Biosci Rep (2022) 42 (1): BSR20211522.

DOI: https://doi.org/10.1042/BSR20211522

Published: 11 January 2022

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Regucalcin ameliorates doxorubicin-induced cytotoxicity in Cos-7 kidney cells and translocates from the nucleus to the mitochondria

Noor A. Mohammed, Israa J. Hakeem, Nikolas Hodges, Francesco Michelangeli

Biosci Rep (2022) 42 (1): BSR20211464.

DOI: https://doi.org/10.1042/BSR20211464

Published: 06 January 2022

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High-dose dexamethasone injection disordered metabolism and multiple protein kinases expression in the mouse kidney

Zaikuan Zhang, Yingchun Ran, Lei Xu, Zheng Pan, Yajun Xie

Biosci Rep (2021) 41 (11): BSR20211847.

DOI: https://doi.org/10.1042/BSR20211847

Published: 18 November 2021

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Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects

Xinhui Liu, Ruyu Deng, Xian Wei, Yuzhi Wang, Jiali Weng, Yunlan Lao, Jiandong Lu, Guoliang Xiong, Shunmin Li

Biosci Rep (2021) 41 (10): BSR20211598.

DOI: https://doi.org/10.1042/BSR20211598

Published: 22 October 2021

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Computational and in vitro experimental analyses of the Anti-COVID-19 potential of Mortaparib and Mortaparib Plus

Vipul Kumar, Anissa Nofita Sari, Hazna Noor Meidinna, Jaspreet Kaur Dhanjal, Chandru Subramani, Brohmomoy Basu, Sunil C Kaul, Sudhanshu Vrati, Durai Sundar, Renu Wadhwa

Biosci Rep (2021) BSR20212156.

DOI: https://doi.org/10.1042/BCJ20210626

Published: 04 October 2021

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Cinnamic acid inhibits cell viability, invasion, and glycolysis in primary endometrial stromal cells by suppressing NF-κB-induced transcription of PKM2

Qiuwen Yao, Guiying Jing, Xiaowen Zhang, Meiling Li, Qihuan Yao, Longhui Wang

Biosci Rep (2021) BSR20211828.

DOI: https://doi.org/10.1042/BSR20211828

Published: 09 September 2021

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Parathyroid hormone promotes the osteogenesis of lipopolysaccharide-induced human bone marrow mesenchymal stem cells through the JNK MAPK pathway

Ziyue Qin, Shu Hua, Huifen Chen, Zhuo Wang, Haoran Wang, Jiamin Xu, Yuli Wang, Wu Chen, Weina Zhou

Biosci Rep (2021) 41 (8): BSR20210420.

DOI: https://doi.org/10.1042/BSR20210420

Published: 20 August 2021

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Effect of Chaihu-jia-Longgu-Muli decoction on withdrawal symptoms in rats with methamphetamine-induced conditioned place preference

Zifa Li, Yuchen Qi, Kun Liu, Yiming Cao, Hao Zhang, Chunhong Song, Hualiang Deng

Biosci Rep (2021) 41 (8): BSR20211376.

DOI: https://doi.org/10.1042/BSR20211376

Published: 20 August 2021

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Exploration of the molecular targets and mechanisms of suxiao xintong dropping pills for myocardial infarction by network pharmacology method

Daqiu Chen, Yanqing Wu, Yixing Chen, Qiaoxing Chen, Xianhua Ye, Shanghua Xu, Shunxiang Luo

Biosci Rep (2021) 41 (8): BSR20204211.

DOI: https://doi.org/10.1042/BSR20204211

Published: 05 August 2021

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Gualou Xiebai Banxia decoction ameliorates Poloxamer 407-induced hyperlipidemia

Mingzhu Luo, Rong Fan, Xiaoming Wang, Junyu Lu, Ping Li, Wenbin Chu, Yonghe Hu, Xuewei Chen

Biosci Rep (2021) 41 (6): BSR20204216.

DOI: https://doi.org/10.1042/BSR20204216

Published: 14 June 2021

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The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis

Liuting Zeng, Ganpeng Yu, Wensa Hao, Kailin Yang, Hua Chen

Biosci Rep (2021) 41 (6): BSR20210817.

DOI: https://doi.org/10.1042/BSR20210817

Published: 10 June 2021

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Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway

Yonggang Xu, Rong Fang, Jie Shao, Zihao Cai

Biosci Rep (2021) 41 (6): BSR20210093.

DOI: https://doi.org/10.1042/BSR20210093

Published: 10 June 2021

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Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy

Tareq Saleh, Ahmad Alhesa, Mahmoud Al-Balas, Omar Abuelaish, Ahmad Mansour, Heyam Awad, Mohammed El-Sadoni, Valerie J. Carpenter, Bilal Azab

Biosci Rep (2021) 41 (5): BSR20210079.

DOI: https://doi.org/10.1042/BSR20210079

Published: 20 May 2021

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Shensu IV prevents glomerular podocyte injury in nephrotic rats via promoting lncRNA H19/DIRAS3-mediated autophagy

Yong Huang, Yaqian Huang, Yehua Zhou, Jie Cheng, Chanjun Wan, Maohong Wang, Chiheng Pi, Guoqing Wu, Weiguo Song

Biosci Rep (2021) 41 (5): BSR20203362.

DOI: https://doi.org/10.1042/BSR20203362

Published: 04 May 2021

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Comparative assessment of the bactericidal effect of nanoparticles of copper oxide, silver, and chitosan-silver against Escherichia coli infection in broilers

Eman I. Hassanen, Eman A. Morsy, Ahmed M. Hussien, Khaled Y. Farroh, Merhan E. Ali

Biosci Rep (2021) 41 (4): BSR20204091.

DOI: https://doi.org/10.1042/BSR20204091

Published: 16 April 2021

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Molecular mechanisms of An-Chuan Granule for the treatment of asthma based on a network pharmacology approach and experimental validation

Xiao-Li Chen, Qing-Ling Xiao, Zhong-Hua Pang, Cheng Tang, Qi-Yong Zhu

Biosci Rep (2021) 41 (3): BSR20204247.

DOI: https://doi.org/10.1042/BSR20204247

Published: 24 March 2021

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Dexmedetomidine attenuates lipopolysaccharide-induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway

Fei Tong, Wenchao Shen, Pengtao Song, Jiafeng Song, Yonghe Hu, Feifan Liu, Zhipeng Meng, Jing Liu

Biosci Rep (2021) 41 (3): BSR20204279.

DOI: https://doi.org/10.1042/BSR20204279

Published: 04 March 2021

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The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice

Shengyun Zhu, Jing Liang, Feng Zhu, Xue Zhang, Mengdi Xu, Kai Zhao, Lingyu Zeng, Kailin Xu

Biosci Rep (2021) 41 (3): BSR20202993.

DOI: https://doi.org/10.1042/BSR20202993

Published: 02 March 2021

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Role of ABCB1 in mediating chemoresistance of triple-negative breast cancers

Yomna S. Abd El-Aziz, Andrew J. Spillane, Patric J. Jansson, Sumit Sahni

Biosci Rep (2021) 41 (2): BSR20204092.

DOI: https://doi.org/10.1042/BSR20204092

Published: 17 February 2021

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Exploring the mechanism of aidi injection for lung cancer by network pharmacology approach and molecular docking validation

Zhenjie Zhuang, Tong Lin, Lixia Luo, Weixin Zhou, Junmao Wen, Haifu Huang, Zhanhua Liu, Lizhu Lin

Biosci Rep (2021) 41 (2): BSR20204062.

DOI: https://doi.org/10.1042/BSR20204062

Published: 12 February 2021

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Exploring the mechanism of (-)-Epicatechin on premature ovarian insufficiency based on network pharmacology and experimental evaluation

Fei Yan, Qi Zhao, Huanpeng Gao, Xiaomei Wang, Ke Xu, Yishu Wang, Fuguo Han, Qingfei Liu, Yun Shi

Biosci Rep (2021) 41 (2): BSR20203955.

DOI: https://doi.org/10.1042/BSR20203955

Published: 12 February 2021

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Revealing mechanism of Caulis Sargentodoxae for the treatment of ulcerative colitis based on network pharmacology approach

Bin Liu, Xin Zheng, Jiajun Li, Xiong Li, Ruimei Wu, Jing Yang, Wei Liu, Gaoping Zhao

Biosci Rep (2021) 41 (1): BSR20204005.

DOI: https://doi.org/10.1042/BSR20204005

Published: 29 January 2021

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The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro

Bolun Wang, Haohui Guo, Tianxiang Geng, Kening Sun, Liang Zhang, Zhidong Lu, Qunhua Jin

Biosci Rep (2021) 41 (1): BSR20203003.

DOI: https://doi.org/10.1042/BSR20203003

Published: 29 January 2021

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Effects of 22 traditional anti-diabetic medicinal plants on DPP-IV enzyme activity and glucose homeostasis in high-fat fed obese diabetic rats

Prawej Ansari, Mary P. Hannon-Fletcher, Peter R. Flatt, Yasser H.A. Abdel-Wahab

Biosci Rep (2021) 41 (1): BSR20203824.

DOI: https://doi.org/10.1042/BSR20203824

Published: 22 January 2021

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Red algae natural products for prevention of lipopolysaccharides (LPS)-induced liver and kidney inflammation and injuries

Asmaa Nabil-Adam, Mohamed A. Shreadah

Biosci Rep (2021) 41 (1): BSR20202022.

DOI: https://doi.org/10.1042/BSR20202022

Published: 15 January 2021

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Toxicity profiling of the ethanolic extract of Citrullus lanatus seed in rats: behavioral, biochemical and histopathological aspects

Sateesh Belemkar, Parshuram Nivrutti Shendge

Biosci Rep (2021) 41 (1): BSR20202345.

DOI: https://doi.org/10.1042/BSR20202345

Published: 08 January 2021

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Pharmacological insights into Merremia vitifolia (Burm.f.) Hallier f. leaf for its antioxidant, thrombolytic, anti-arthritic and anti-nociceptive potential

Sahida Akter, Israt Jahan, Mst. Riniara Khatun, Mohammad Forhad Khan, Laiba Arshad, Md. Jakaria, Md. Areeful Haque

Biosci Rep (2021) 41 (1): BSR20203022.

DOI: https://doi.org/10.1042/BSR20203022

Published: 07 January 2021

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GanDouLing promotes proliferation and differentiation of neural stem cells in the mouse model of Wilson’s disease

Ting Dong, Ming-cai Wu, Lu-lu Tang, Hai-lin Jiang, Ping Zhou, Chun-jun Kuang, Li-wei Tian, Wen-ming Yang

Biosci Rep (2021) 41 (1): BSR20202717.

DOI: https://doi.org/10.1042/BSR20202717

Published: 05 January 2021

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β-glucan from Lentinus edodes inhibits breast cancer progression via the Nur77/HIF-1α axis

Xiuru Zhang, Tingting Li, Shuwen Liu, Yiming Xu, Minjun Meng, Xiumin Li, Zhichao Lin, Qici Wu, Yu Xue, Yutian Pan, Gulimiran Alitongbieke

Biosci Rep (2020) 40 (12): BSR20201006.

DOI: https://doi.org/10.1042/BSR20201006

Published: 14 December 2020

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Efficacy of tripterygium glycosides combined with ARB on diabetic nephropathy: a meta-analysis

Xue Wu, Youye Huang, Yao Zhang, Chunling He, Yongli Zhao, Lizhuo Wang, Jialin Gao

Biosci Rep (2020) 40 (11): BSR20202391.

DOI: https://doi.org/10.1042/BSR20202391

Published: 13 November 2020

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Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide

Abdulla A.-B. Badawy

Biosci Rep (2020) 40 (10): BSR20202856.

DOI: https://doi.org/10.1042/BSR20202856

Published: 30 October 2020

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Zanthoxylum nitidum extract attenuates BMP-2-induced inflammation and hyperpermeability

Tao Hu, Zhiwen Luo, Kai Li, Shanjin Wang, Desheng Wu

Biosci Rep (2020) 40 (10): BSR20201098.

DOI: https://doi.org/10.1042/BSR20201098

Published: 23 October 2020

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The relationship between intestinal goblet cells and the immune response

Mingming Zhang, Chenchen Wu

Biosci Rep (2020) 40 (10): BSR20201471.

DOI: https://doi.org/10.1042/BSR20201471

Published: 16 October 2020

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Madecassoside protects retinal pigment epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis through the activation of Nrf2/HO-1 pathway

Jinzi Zhou, Fenghua Chen, Aimin Yan, Xiaobo Xia

Biosci Rep (2020) 40 (10): BSR20194347.

DOI: https://doi.org/10.1042/BSR20194347

Published: 14 October 2020

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Experimental evidence and network pharmacology-based analysis reveal the molecular mechanism of Tongxinluo capsule administered in coronary heart diseases

Guode Li, Qingbo Xu, Kedong Han, Wenhe Yan, Chaopei Huang

Biosci Rep (2020) 40 (10): BSR20201349.

DOI: https://doi.org/10.1042/BSR20201349

Published: 13 October 2020

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Synthesis of new pyrazolone and pyrazole-based adamantyl chalcones and antimicrobial activity

Rawan Al-Saheb, Sami Makharza, Feras Al-battah, Rajab Abu-El-Halawa, Tawfeq Kaimari, Omar S. Abu Abed

Biosci Rep (2020) 40 (9): BSR20201950.

DOI: https://doi.org/10.1042/BSR20201950

Published: 24 September 2020

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Emodin ameliorates renal injury in BXSB mice by modulating TNF-α/ICAM-1

Xinlu Yuan, Binbin Dai, Liyan Yang, Beiduo Lin, Enqin Lin, Yangbin Pan

Biosci Rep (2020) 40 (9): BSR20202551.

DOI: https://doi.org/10.1042/BSR20202551

Published: 18 September 2020

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Antimicrobial peptides from Capsicum chinense fruits: agronomic alternatives against phytopathogenic fungi

Layrana de Azevedo dos Santos, Gabriel Bonan Taveira, Marciele Souza da Silva, Rodrigo da Silva Gebara, Lídia da Silva Pereira, Jonas Perales, André Teixeira-Ferreira, Érica de Oliveira Mello, André de Oliveira Carvalho, Rosana Rodrigues, Valdirene Moreira Gomes

Biosci Rep (2020) 40 (8): BSR20200950.

DOI: https://doi.org/10.1042/BSR20200950

Published: 21 August 2020

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