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Keywords: ASCT2
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Articles
Biosci Rep (2024) 44 (3): BSR20232035.
Published: 12 March 2024
... exerts an effect on EC via glutamine metabolism is unknown. In the present study, we found that P4 could inhibit glutamine metabolism in EC cells and down-regulate the expression of the glutamine transporter ASCT2. This regulation of ASCT2 affects the uptake of glutamine. Furthermore, the in vivo...
Articles
Biosci Rep (2022) 42 (3): BSR20212171.
Published: 16 March 2022
...Wenbin Wang; Haihua Pan; Feihua Ren; Hongxia Chen; Ping Ren Some tumor cells have a high rate of glutamine uptake and exhibit glutamine addiction. Alanine-serine cysteine-preferring transporter 2 (ASCT2) is a major mediator of glutamine supply in many tumor cells, but the underlying effects...
Includes: Supplementary data