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Keywords: Age-related macular degeneration
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Articles

Complement family member CFI polymorphisms and AMD susceptibility from a comprehensive analysis

Qianqian Yu, Jing Zhu, Yong Yao, Chao Sun
Journal: Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200406.
https://doi.org/10.1042/BSR20200406
Published: 09 April 2020
... macular degeneration complement factor I meta-analysis polymorphism risk Age-related macular degeneration (AMD) is a retinal degenerative disease that is an important cause of blindness and central vision loss in the elderly who are over 55 years [ 1 , 2 ]. The incidence rate is 13...
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Includes: Supplementary data
Articles

Protective effects of delphinidin against H 2 O 2 –induced oxidative injuries in human retinal pigment epithelial cells

Timin Ni, Wanju Yang, Yiqiao Xing
Journal: Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190689.
https://doi.org/10.1042/BSR20190689
Published: 15 August 2019
...Timin Ni; Wanju Yang; Yiqiao Xing Age-related macular degeneration (AMD) is now one of the leading causes of blindness in the elderly population and oxidative stress-induced damage to retinal pigment epithelial (RPE) cells occurs as part of the pathogenesis of AMD. In the present study, we...
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Articles

New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3

Elizabeth Rodriguez, Pavithra M. Rallapalli, Amy J. Osborne, Stephen J. Perkins
Journal: Bioscience Reports
Biosci Rep (2014) 34 (5): e00146.
https://doi.org/10.1042/BSR20140117
Published: 22 October 2014
...Elizabeth Rodriguez; Pavithra M. Rallapalli; Amy J. Osborne; Stephen J. Perkins aHUS (atypical haemolytic uraemic syndrome), AMD (age-related macular degeneration) and other diseases are associated with defective AP (alternative pathway) regulation. CFH (complement factor H), CFI (complement factor...
View article titled, New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3
Open the PDF for New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3 in another window
Includes: Supplementary data