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Keywords: Apoptosis
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Biosci Rep (2024) 44 (3): BSR20231682.
Published: 21 March 2024
...Takako Nagata; Yuning George Huang Acute alcoholic hepatitis (AAH) from binge drinking is a serious disease. It is associated with a high mortality rate, especially among young adults. Apoptosis is known to be a primary cause of liver damage, and it can be induced by either intrinsic signaling...
Includes: Supplementary data
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Biosci Rep (2024) 44 (2): BSR-2016-0165_RET.
Published: 28 February 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Akt apoptosis cell cycle Cucurbitacin mTOR signalling osteosarcoma PI3K...
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Biosci Rep (2023) 43 (9): BSR20230014.
Published: 05 September 2023
... the effects of miR-21 and homeodomain interacting protein kinase 3 (HIPK3) on cardiomyocyte apoptosis induced by hypoxia/reoxygenation (H/R) in vitro . To this end, the rat cardiomyocyte H9C2 cell line was exposed to H/R and the roles of miR-21 and HIPK3 in regulating cell viability and apoptosis were...
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Biosci Rep (2023) 43 (2): BSR-2017-1150_EOC.
Published: 09 February 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis cell proliferation growth arrest-specific 5 inflammasome long...
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Biosci Rep (2023) 43 (1): BSR-2019-1050_RET.
Published: 30 January 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis cardiotoxicity doxorubicin long non-coding RNA SNHG1 niR-195...
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Biosci Rep (2022) 42 (12): BSR20222171.
Published: 22 December 2022
...João Pessoa Cytochrome c (cyt c ) is an electron transporter of the mitochondrial respiratory chain. Upon permeabilization of the mitochondrial outer membrane, cyt c is released into the cytoplasm, where it triggers the intrinsic pathway of apoptosis. Cytoplasmic cyt c can further reach...
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Biosci Rep (2022) 42 (9): BSR-2019-1062_RET.
Published: 21 September 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Apoptosis Breast cancer Cosmc Metastasis Proliferation Tn and T glycans...
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Biosci Rep (2022) 42 (6): BSR20220119.
Published: 17 June 2022
... BY) . apoptosis caspase dimerization fluorescence spectroscopy protein folding zebrafish The caspase family is an attractive model to examine the evolution of protein folding landscapes. Caspase genes predate multicellularity and are widely present in eukaryotes [ 1 ]. Caspases are thought to have...
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Biosci Rep (2022) 42 (3): BSR20212171.
Published: 16 March 2022
... -nitroanilide (GPNA) and silenced the expression of ASCT2 with specific shRNAs. We found that the growth of PC cells was significantly inhibited. Additionally, knockdown of ASCT2 induced apoptosis through the Akt/mTOR signaling pathway. Furthermore, the loss of ASCT2 in BxPC-3 cell xenografts significantly...
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Biosci Rep (2022) 42 (3): BSR20210640.
Published: 16 March 2022
... healing. However, little is known about the mechanism underlying high glucose (HG)-induced decrease in tendon fibroblasts viability. In the present study, the rat models of DFU were established, and collagen deposition, autophagy activation and cell apoptosis in tendon tissues were assessed using...
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Biosci Rep (2022) 42 (2): BSR20190878.
Published: 09 February 2022
... assays. Cell migration and invasion were investigated with a transwell assay. Cell apoptosis was probed with flow cytometry. The expression of apoptosis-associated proteins was examined with Western blots. Result: Combination treatment decreased breast cancer cell viability, colony formation, cell...
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Biosci Rep (2022) 42 (1): BSR20211464.
Published: 06 January 2022
... Cos-7 cells as kidney cell model. Cos-7 cells were exposed to DOX for a period of 24 h over a range of concentrations, and the LC 50 was determined to be 7 µM. Further investigations showed that cell death was mainly via apoptosis involving Ca 2+ and caspase 9, in addition to autophagy. Regucalcin...
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Biosci Rep (2021) 41 (12): BSR20211577.
Published: 17 December 2021
... 10 2021 22 11 2021 07 12 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis Cancer cell survival...
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Biosci Rep (2021) 41 (10): BSR-2019-0503_COR.
Published: 29 October 2021
... apoptosis bladder cancer cell cycle ENO1 This Correction follows an Expression of Concern relating to this article previously published by Portland Press. The authors of the original article “Up-regulated ENO1 promotes the bladder cancer cell growth and proliferation via regulating...
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Biosci Rep (2021) 41 (9): BSR20202232.
Published: 03 September 2021
... in the progression of various diseases, including DCM. The purpose of the present study was to explore the role of lncRNA GAS5 in high glucose (HG)-induced cardiomyocyte injury and apoptosis. Materials and methods: We constructed HG-induced AC16 cardiomyocytes and a streptozotocin (STZ)-induced rat diabetes model...
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Biosci Rep (2021) 41 (7): BSR20204177.
Published: 28 July 2021
... migration, invasion and promoted apoptosis of AGS cells. More importantly, microRNA-506-5p (miR-506-5p) was predicted as a direct target of SNHG15 by binding its 3′-UTR and further verified using luciferase reporter assay. Meanwhile, the results of rescue experiments revealed that knockdown of miR-506-5p...
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Biosci Rep (2021) 41 (7): BSR20211143.
Published: 12 July 2021
... of J. communis extract (JCo extract) on HCC in vitro and in vivo . In the present study, we found that JCo extract inhibited the growth of human HCC cells by inducing cell cycle arrest at the G 0 /G 1 phase, extensive apoptosis and suppressing metastatic protein expressions in HCC cells. Moreover...
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Biosci Rep (2021) 41 (4): BSR20203905.
Published: 30 April 2021
... of cancers. The aim of the present study is to explore the roles of WT161 in osteosarcoma and its underlying mechanisms. Methods: The anti-proliferative effect of WT161 on osteosarcoma cells was examined using MTT assay and colony formation assay. Cell apoptosis was analyzed using flow cytometer...
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Biosci Rep (2021) 41 (4): BSR-20180861_COR.
Published: 27 April 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis brain cadmium Fragaria ananassa oxidative stress This Correction follows an Expression of Concern relating to this article previously published by Portland Press. ...
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Biosci Rep (2021) 41 (4): BSR20203091.
Published: 22 April 2021
... significantly reduced total blastocyst cell numbers ( P <0.001) and increased apoptosis of blastocyst cells ( P <0.001). Moreover, HU exposure reduced the rate of development of two-celled, four- to eight-celled, blastocyst, and hatching stages after parthenogenetic activation ( P <0.05). Our findings...
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Biosci Rep (2021) 41 (4): BSR-20181859_RET.
Published: 19 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis breast cancer GAS5 miR-221/222 This article is being...
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Biosci Rep (2021) 41 (4): BSR-20192639_RET.
Published: 19 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . acute lung injury apoptosis inflammation PPARγ PTEN/β-catenin pathway...
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Biosci Rep (2021) 41 (4): BSR20203690.
Published: 31 March 2021
... calcium-dependent cellular pathways including neuronal function, muscle contraction, signal transduction, cell differentiation, proliferation, and apoptosis. Research suggests that C1 and C2 perform similar functions due to their structurally highly similar isoforms. Increasing evidence suggests that C1...